Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02687
CAS Number:
142994-45-4
Fmoc-3-(3'-pyridyl)-D-alanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Ala(3'-pyridyl)-OH, Fmoc-β-(3'-pyridyl)-D-Ala-OH, Fmoc-(R-2-amino-3-(3'-pyridyl)propanoic acid
Documents
$86.23 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-3-(3'-pyridyl)-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the incorporation of a pyridine ring, enhances its reactivity and compatibility with various coupling reagents, making it an excellent choice for researchers focused on developing complex peptide sequences.

In the pharmaceutical industry, Fmoc-3-(3'-pyridyl)-D-alanine serves as a building block for bioactive peptides, which can be pivotal in therapeutic applications, including cancer treatment and antimicrobial agents. Its ability to facilitate the synthesis of peptides with specific biological activities positions it as a valuable tool for medicinal chemists and biochemists alike. The compound's stability and ease of use in solid-phase peptide synthesis further contribute to its appeal, allowing for efficient and reproducible results in laboratory settings.

Synonyms
Fmoc-D-Ala(3'-pyridyl)-OH, Fmoc-β-(3'-pyridyl)-D-Ala-OH, Fmoc-(R-2-amino-3-(3'-pyridyl)propanoic acid
CAS Number
142994-45-4
Purity
≥ 99% (HPLC)
Molecular Formula
C23H20N2O4
Molecular Weight
388.4
MDL Number
MFCD00080267
PubChem ID
3707894
Melting Point
164 - 169 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = 11 ± 1 ° (C=1.034 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Ala(3'-pyridyl)-OH, Fmoc-β-(3'-pyridyl)-D-Ala-OH, Fmoc-(R-2-amino-3-(3'-pyridyl)propanoic acid
CAS Number
142994-45-4
Purity
≥ 99% (HPLC)
Molecular Formula
C23H20N2O4
Molecular Weight
388.4
MDL Number
MFCD00080267
PubChem ID
3707894
Melting Point
164 - 169 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = 11 ± 1 ° (C=1.034 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-(3'-pyridyl)-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure makes it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors or pathways involving pyridine derivatives.
  • Bioconjugation: Researchers use this compound to create bioconjugates, which can enhance the delivery of therapeutic agents, improving their efficacy and reducing side effects.
  • Research in Neuroscience: The pyridine moiety is significant in neuroscience research, where it can be utilized to study neuroactive compounds and their interactions with neuronal receptors.
  • Analytical Chemistry: It is employed in analytical methods to detect and quantify specific biomolecules, providing a reliable way to monitor biological processes in various samples.

Citations