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Catalog Number:
02663
CAS Number:
103478-63-3
Fmoc-N-methyl-D-leucine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-N-Me-D-Leu-OH
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Product Information

Fmoc-N-methyl-D-leucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its unique structure not only enhances the stability of the peptide chains but also facilitates the introduction of various functional groups, making it an invaluable tool for researchers in medicinal chemistry and biochemistry.

In practical applications, Fmoc-N-methyl-D-leucine is particularly beneficial in the synthesis of bioactive peptides and pharmaceuticals, where precise control over amino acid sequences is crucial. Its ability to improve solubility and stability in various solvents further enhances its utility in laboratory settings. Researchers have successfully employed this compound in the development of peptide-based therapeutics, showcasing its potential in advancing drug discovery and development processes. With its robust performance and adaptability, Fmoc-N-methyl-D-leucine stands out as a key ingredient for professionals aiming to innovate in peptide chemistry.

Synonyms
Fmoc-N-Me-D-Leu-OH
CAS Number
103478-63-3
Purity
≥ 99% (HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.4
MDL Number
MFCD00235877
PubChem ID
4279716
Melting Point
110-120 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +22 ± 3º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-N-Me-D-Leu-OH
CAS Number
103478-63-3
Purity
≥ 99% (HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.4
MDL Number
MFCD00235877
PubChem ID
4279716
Melting Point
110-120 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +22 ± 3º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-N-methyl-D-leucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides.
  • Drug Development: It plays a significant role in pharmaceutical research, helping to develop new drugs by modifying peptide structures to enhance their efficacy and stability.
  • Biotechnology: In the field of biotechnology, it is used to produce peptide-based therapeutics, which can be crucial for treating various diseases, including cancer and metabolic disorders.
  • Protein Engineering: Researchers utilize this compound in protein engineering to introduce specific amino acid modifications, improving protein function and interaction.
  • Analytical Chemistry: It is also employed in analytical methods for characterizing peptides and proteins, providing insights into their structure and function.

Citations