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Catalog Number:
02650
CAS Number:
84000-07-7
Fmoc-N-methyl-L-alanine
Purity:
≥ 99% (Chiral HPLC)
Synonym(s):
Fmoc-N-Me-L-Ala-OH
Documents
$28.04 /1G
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Product Information

Fmoc-N-methyl-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an excellent choice for researchers looking to streamline their synthesis processes. The N-methyl substitution enhances its stability and solubility, which are critical attributes for various applications in medicinal chemistry and biochemistry.

In practical applications, Fmoc-N-methyl-L-alanine is particularly valuable in the production of peptide-based therapeutics and in the development of novel biomaterials. Its ability to facilitate the formation of complex peptide sequences makes it a preferred choice among chemists and researchers. Additionally, its compatibility with automated synthesizers allows for high-throughput synthesis, significantly increasing productivity in laboratory settings. By incorporating this compound into your research or production processes, you can achieve greater efficiency and precision in your peptide synthesis endeavors.

Synonyms
Fmoc-N-Me-L-Ala-OH
CAS Number
84000-07-7
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C19H19NO4
Molecular Weight
325.3
MDL Number
MFCD00153384
PubChem ID
3912665
Melting Point
155 - 157 ?C
Appearance
White or off-white powder
Optical Rotation
[a]D20 = -20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-N-Me-L-Ala-OH
CAS Number
84000-07-7
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C19H19NO4
Molecular Weight
325.3
MDL Number
MFCD00153384
PubChem ID
3912665
Melting Point
155 - 157 ?C
Appearance
White or off-white powder
Optical Rotation
[a]D20 = -20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-N-methyl-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of N-methylation, which can enhance the stability and bioactivity of the resulting peptides.
  • Drug Development: Researchers use Fmoc-N-methyl-L-alanine in the development of pharmaceutical compounds, particularly in creating more effective drug candidates with improved pharmacological properties.
  • Bioconjugation: It plays a significant role in bioconjugation processes, where it can be used to attach biomolecules to drugs or imaging agents, enhancing their targeting capabilities in therapeutic applications.
  • Protein Engineering: This compound is instrumental in protein engineering, enabling scientists to modify proteins for better functionality, stability, or specificity in various applications, including diagnostics and therapeutics.
  • Research in Neuroscience: Fmoc-N-methyl-L-alanine is also explored in neuroscience research, where it may be used to study the effects of methylation on neurotransmitter activity and receptor interactions.

Citations