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Catalog Number:
02634
CAS Number:
27460-51-1
Acetyl-L-proline methyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Ac-L-Pro-OMe, (S)-Acetyl-pyrrolidine-2-carboxylic acid methyl ester
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Product Information

Acetyl-L-proline methyl ester is a versatile compound widely recognized for its applications in the pharmaceutical and chemical research sectors. This compound, a derivative of proline, exhibits unique properties that make it valuable in the synthesis of various bioactive molecules. Its structure allows for easy modification, facilitating the development of novel therapeutic agents, particularly in the fields of neuropharmacology and peptide synthesis. Researchers often utilize Acetyl-L-proline methyl ester as a building block in the preparation of cyclic peptides and other complex organic compounds, enhancing the efficiency of their synthetic pathways.

In addition to its role in organic synthesis, Acetyl-L-proline methyl ester has shown potential in medicinal chemistry, particularly for its neuroprotective properties. Its ability to cross the blood-brain barrier makes it a candidate for further exploration in treatments for neurodegenerative diseases. The compound's favorable solubility and stability profile also contribute to its appeal in formulation development. With its broad range of applications, Acetyl-L-proline methyl ester stands out as a crucial tool for researchers aiming to innovate in drug discovery and development.

Synonyms
Ac-L-Pro-OMe, (S)-Acetyl-pyrrolidine-2-carboxylic acid methyl ester
CAS Number
27460-51-1
Purity
≥ 98% (HPLC)
Molecular Formula
C8H13NO3
Molecular Weight
171.2
MDL Number
MFCD00037338
PubChem ID
550999
Appearance
Yellowish to colorless or pale yellow liquid
Optical Rotation
[a]20D = -63 to -67 ° (C=0.5 in CH2Cl2)20D = -56 ± 1 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Synonyms
Ac-L-Pro-OMe, (S)-Acetyl-pyrrolidine-2-carboxylic acid methyl ester
CAS Number
27460-51-1
Purity
≥ 98% (HPLC)
Molecular Formula
C8H13NO3
Molecular Weight
171.2
MDL Number
MFCD00037338
PubChem ID
550999
Appearance
Yellowish to colorless or pale yellow liquid
Optical Rotation
[a]20D = -63 to -67 ° (C=0.5 in CH2Cl2)20D = -56 ± 1 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Acetyl-L-proline methyl ester is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in the synthesis of peptides, offering enhanced stability and solubility compared to other amino acid derivatives, which is crucial for drug formulation.
  • Biochemical Research: Researchers employ this compound in studies related to protein folding and enzyme activity, helping to understand complex biological processes.
  • Cosmetic Formulations: The compound is incorporated into skincare products for its moisturizing properties, providing a smoother texture and improved skin hydration.
  • Food Industry: It acts as a flavor enhancer in food products, contributing to the overall taste profile while maintaining safety and regulatory compliance.

Citations