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Catalog Number:
02632
CAS Number:
59785-68-1
Acetyl-D-proline
Purity:
≥ 98% (Assay)
Synonym(s):
Acetyl-D-proline, (R-Acetyl-pyrrolidine-2-carboxylic acid
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Product Information

Acetyl-D-proline is a versatile amino acid derivative that plays a significant role in various fields, including pharmaceuticals and biochemistry. This compound is recognized for its unique structural properties, which enhance its functionality in peptide synthesis and drug development. Its acetyl group contributes to increased lipophilicity, making it an excellent candidate for improving the bioavailability of therapeutic agents. Researchers often utilize Acetyl-D-proline in the synthesis of cyclic peptides and as a building block for more complex molecular structures, facilitating advancements in medicinal chemistry.

In addition to its applications in drug formulation, Acetyl-D-proline is also valuable in the study of protein folding and enzyme activity, providing insights into biological processes. Its ability to act as a chiral auxiliary further enhances its utility in asymmetric synthesis, making it a preferred choice for chemists aiming to create enantiomerically pure compounds. With its broad range of applications and benefits, Acetyl-D-proline stands out as a crucial tool for researchers and industry professionals alike.

Synonyms
Acetyl-D-proline, (R-Acetyl-pyrrolidine-2-carboxylic acid
CAS Number
59785-68-1
Purity
≥ 98% (Assay)
Molecular Formula
C7H11NO3
Molecular Weight
157.2
MDL Number
MFCD00080841
PubChem ID
322640
Melting Point
111-117 °C
Appearance
White crystal powder
Optical Rotation
[α]D20 = +113 ± 2º (C=2 in H2O)
Conditions
Store at 0-8 °C
General Information
Synonyms
Acetyl-D-proline, (R-Acetyl-pyrrolidine-2-carboxylic acid
CAS Number
59785-68-1
Purity
≥ 98% (Assay)
Molecular Formula
C7H11NO3
Molecular Weight
157.2
MDL Number
MFCD00080841
PubChem ID
322640
Melting Point
111-117 °C
Appearance
White crystal powder
Optical Rotation
[α]D20 = +113 ± 2º (C=2 in H2O)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Acetyl-D-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of cyclic peptides that have enhanced stability and bioactivity.
  • Pharmaceutical Development: It is used in drug formulation, especially in creating compounds that target specific biological pathways, offering potential therapeutic benefits in treating various diseases.
  • Protein Engineering: Researchers leverage acetyl-D-proline to modify protein structures, improving their functionality and interaction with other biomolecules, which is crucial in biochemistry and molecular biology.
  • Analytical Chemistry: This chemical acts as a reference standard in analytical methods, helping to ensure accuracy and reliability in the quantification of similar compounds in complex mixtures.
  • Cosmetic Formulations: Its unique properties make it an ingredient in cosmetic products, enhancing skin absorption and providing moisturizing benefits, appealing to the beauty and personal care industry.

Citations