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Catalog Number:
02602
CAS Number:
130309-33-0
Fmoc-(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Tic-OH
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Product Information

Fmoc-(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is a versatile compound widely utilized in peptide synthesis and drug development. This compound, characterized by its unique structure, serves as a protective group in the synthesis of amino acids and peptides, facilitating the formation of complex molecular architectures. Its ability to stabilize intermediates during chemical reactions makes it invaluable in organic synthesis, particularly in the pharmaceutical industry where precision and efficiency are paramount. Researchers appreciate its role in enhancing the solubility and stability of peptides, which is crucial for developing effective therapeutic agents.

Moreover, Fmoc-(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid stands out due to its favorable properties, such as high compatibility with various coupling reagents and mild deprotection conditions. This allows for streamlined workflows in laboratories, reducing the time and resources needed for synthesis. Its application extends to the development of novel compounds with potential therapeutic effects, making it a key player in advancing medicinal chemistry and drug discovery. With its robust performance and reliability, this compound is an essential tool for researchers aiming to innovate in the field of biochemistry.

Synonyms
Fmoc-D-Tic-OH
CAS Number
130309-33-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H21NO4
Molecular Weight
399.4
MDL Number
MFCD00144345
PubChem ID
6957977
Melting Point
152 - 168 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -26 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Tic-OH
CAS Number
130309-33-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H21NO4
Molecular Weight
399.4
MDL Number
MFCD00144345
PubChem ID
6957977
Melting Point
152 - 168 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -26 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique structure is beneficial in the design of novel pharmaceuticals, particularly in creating compounds that target specific biological pathways.
  • Bioconjugation: The chemical can be used to attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutic agents.
  • Research in Neuroscience: Due to its structural similarity to neurotransmitters, it is explored in studies related to neuropharmacology and the development of treatments for neurological disorders.
  • Organic Synthesis: This compound is a valuable intermediate in the synthesis of complex organic molecules, making it essential for researchers in organic chemistry and material science.

Citations