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Catalog Number:
02586
CAS Number:
58438-04-3
Boc-3-(2-naphthyl)-L-alanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-L-Ala(2-naphthyl)-OH, Boc-(S)-2-amino-3-(naphthalen-2-yl)propanoic acid, Boc-Ala(2-naphthyl)-OH
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Product Information

Boc-3-(2-naphthyl)-L-alanine is a versatile amino acid derivative that serves as a crucial building block in peptide synthesis and drug development. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers in organic chemistry and pharmaceutical applications. Its unique structure, characterized by the naphthyl group, provides significant advantages in the design of bioactive peptides, allowing for enhanced binding interactions and improved pharmacological properties.

In the pharmaceutical industry, Boc-3-(2-naphthyl)-L-alanine is utilized in the synthesis of peptide-based therapeutics, particularly in the development of inhibitors and modulators for various biological targets. Its ability to facilitate the formation of complex structures makes it invaluable for researchers aiming to create novel compounds with specific biological activities. Moreover, its compatibility with various coupling reagents and methodologies further supports its application in high-throughput screening and drug discovery processes.

Synonyms
Boc-L-Ala(2-naphthyl)-OH, Boc-(S)-2-amino-3-(naphthalen-2-yl)propanoic acid, Boc-Ala(2-naphthyl)-OH
CAS Number
58438-04-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H21NO4
Molecular Weight
315.2
MDL Number
MFCD00079671
PubChem ID
7020907
Melting Point
~ 95 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 45 ± 2 ° (C=2 in EtOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Ala(2-naphthyl)-OH, Boc-(S)-2-amino-3-(naphthalen-2-yl)propanoic acid, Boc-Ala(2-naphthyl)-OH
CAS Number
58438-04-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H21NO4
Molecular Weight
315.2
MDL Number
MFCD00079671
PubChem ID
7020907
Melting Point
~ 95 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 45 ± 2 ° (C=2 in EtOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3-(2-naphthyl)-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for selective reactions and improving yield and purity in pharmaceutical development.
  • Drug Development: Its unique structure makes it valuable in designing novel drugs, particularly in targeting specific receptors, enhancing bioactivity, and improving pharmacokinetic properties.
  • Bioconjugation: The compound is used in bioconjugation processes, linking biomolecules to create targeted therapies, which is crucial in the development of antibody-drug conjugates.
  • Research in Neuroscience: It plays a role in studying neurotransmitter systems, aiding in the understanding of neurological disorders and the development of potential treatments.
  • Material Science: The compound is explored for its potential in creating advanced materials, such as polymers with specific properties, enhancing their application in various industrial processes.

Citations