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Catalog Number:
02579
CAS Number:
132684-59-4
Fmoc-L-homophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-HomoPhe-OH, (S)-2-(Fmoc-amino)-4-phenyl-butyric acid, Fmoc-HomoPhe-OH
Documents
$18.53 /1G
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Product Information

Fmoc-L-homophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an excellent choice for solid-phase peptide synthesis. Researchers appreciate its ability to facilitate the introduction of phenylalanine-like residues into peptides, thereby improving the pharmacological properties of the resulting compounds.

In addition to its role in peptide synthesis, Fmoc-L-homophenylalanine is also employed in the development of novel therapeutics, particularly in the fields of oncology and neurology. Its unique structure allows for the exploration of new peptide-based drugs that can target specific biological pathways. The compound's compatibility with various coupling reagents and its ease of deprotection further enhance its appeal to researchers seeking efficient and effective synthesis methods.

Synonyms
Fmoc-L-HomoPhe-OH, (S)-2-(Fmoc-amino)-4-phenyl-butyric acid, Fmoc-HomoPhe-OH
CAS Number
132684-59-4
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.45
MDL Number
MFCD00077046
PubChem ID
2761467
Melting Point
142 - 159 °C
Appearance
White powder
Optical Rotation
[a]D20 = -9 ± 2 ° (C=1, DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-HomoPhe-OH, (S)-2-(Fmoc-amino)-4-phenyl-butyric acid, Fmoc-HomoPhe-OH
CAS Number
132684-59-4
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.45
MDL Number
MFCD00077046
PubChem ID
2761467
Melting Point
142 - 159 °C
Appearance
White powder
Optical Rotation
[a]D20 = -9 ± 2 ° (C=1, DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-homophenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, particularly in targeting specific biological pathways.
  • Bioconjugation: Fmoc-L-homophenylalanine can be used in bioconjugation processes, facilitating the attachment of peptides to various biomolecules for therapeutic applications.
  • Research in Neuroscience: This compound is employed in studies related to neurotransmitter function and receptor interactions, aiding in the understanding of neurological disorders.
  • Custom Peptide Libraries: It is instrumental in creating diverse peptide libraries for screening potential drug candidates, enhancing the efficiency of drug discovery processes.

Citations