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Fmoc-4-fluoro-D-phenylalanine
Fmoc-4-fluoro-D-phenylalanine is widely utilized in research focused on
- Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of fluorinated amino acids that can enhance the stability and activity of the resulting peptides.
- Drug Development: Its unique properties make it valuable in pharmaceutical research, particularly in the development of drugs targeting specific receptors, where the fluorine atom can improve binding affinity and selectivity.
- Bioconjugation: The compound is used in bioconjugation techniques, where it can be attached to other molecules, such as proteins or antibodies, to create targeted therapies or imaging agents in cancer research.
- Analytical Chemistry: In analytical applications, it can be employed as a derivatizing agent to enhance the detection of amino acids and peptides in various samples, improving sensitivity and specificity in mass spectrometry.
- Research in Neuroscience: Its incorporation into peptide sequences allows researchers to study neuropeptide interactions and signaling pathways, providing insights into neurological disorders and potential therapeutic targets.
General Information
Properties
Safety and Regulations
Applications
Fmoc-4-fluoro-D-phenylalanine is widely utilized in research focused on
- Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of fluorinated amino acids that can enhance the stability and activity of the resulting peptides.
- Drug Development: Its unique properties make it valuable in pharmaceutical research, particularly in the development of drugs targeting specific receptors, where the fluorine atom can improve binding affinity and selectivity.
- Bioconjugation: The compound is used in bioconjugation techniques, where it can be attached to other molecules, such as proteins or antibodies, to create targeted therapies or imaging agents in cancer research.
- Analytical Chemistry: In analytical applications, it can be employed as a derivatizing agent to enhance the detection of amino acids and peptides in various samples, improving sensitivity and specificity in mass spectrometry.
- Research in Neuroscience: Its incorporation into peptide sequences allows researchers to study neuropeptide interactions and signaling pathways, providing insights into neurological disorders and potential therapeutic targets.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.