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Catalog Number:
02563
CAS Number:
4043-88-3
3,4-Dehydro-L-proline
Purity:
≥ 99%
Synonym(s):
3,4-Dehydro-L-Pro-OH, (S-3,4-Dehydro-pyrrolidine-2-carboxylic acid
Documents
$93.14 /100MG
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Product Information

3,4-Dehydro-L-proline is a unique amino acid derivative that plays a significant role in various biochemical applications. This compound is recognized for its structural similarity to proline, making it an essential building block in peptide synthesis and protein engineering. Its distinctive double bond configuration enhances its stability and reactivity, which is particularly beneficial in the development of pharmaceuticals and agrochemicals. Researchers utilize 3,4-Dehydro-L-proline in the synthesis of cyclic peptides and as a chiral building block in asymmetric synthesis, providing a pathway to create complex molecular architectures.

In addition to its applications in synthetic chemistry, this compound has shown promise in the field of medicinal chemistry, where it is explored for its potential therapeutic effects. Its ability to mimic natural amino acids while offering unique properties makes it an attractive candidate for drug design and development. With its versatile applications and advantages over traditional amino acids, 3,4-Dehydro-L-proline is an invaluable asset for researchers and industry professionals seeking innovative solutions in their projects.

Synonyms
3,4-Dehydro-L-Pro-OH, (S-3,4-Dehydro-pyrrolidine-2-carboxylic acid
CAS Number
4043-88-3
Purity
≥ 99%
Molecular Formula
C5H7NO2
Molecular Weight
113.1
MDL Number
MFCD00065964
PubChem ID
97858
Melting Point
238-240 °C
Appearance
White to brown crystalline solid
Optical Rotation
[a]D20 = - 399.4 ± 0.2 ° (C=1, in H2O)
Conditions
Store at 0-8 °C
General Information
Synonyms
3,4-Dehydro-L-Pro-OH, (S-3,4-Dehydro-pyrrolidine-2-carboxylic acid
CAS Number
4043-88-3
Purity
≥ 99%
Molecular Formula
C5H7NO2
Molecular Weight
113.1
MDL Number
MFCD00065964
PubChem ID
97858
Melting Point
238-240 °C
Appearance
White to brown crystalline solid
Optical Rotation
[a]D20 = - 399.4 ± 0.2 ° (C=1, in H2O)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3,4-Dehydro-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of cyclic peptides that have unique biological activities.
  • Pharmaceutical Development: It is used in the design of novel drugs, especially in creating inhibitors for various enzymes, which can lead to advancements in treating diseases like cancer and diabetes.
  • Biochemical Research: Researchers leverage its properties to study protein folding and stability, helping to understand diseases related to protein misfolding.
  • Material Science: The compound finds applications in the development of new materials, such as hydrogels, which are used in drug delivery systems and tissue engineering.
  • Amino Acid Derivatives: It acts as a precursor for synthesizing other amino acid derivatives, which are essential in various biochemical applications and nutritional supplements.

Citations