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Catalog Number:
02562
CAS Number:
161321-36-4
Fmoc-L-cyclohexylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Chg-OH, Fmoc-cyclohexyl-Gly-OH
Documents
$43.87 /1G
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Product Information

Fmoc-L-cyclohexylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a cyclohexyl side chain, which enhances the hydrophobic character of peptides, making it particularly valuable in the design of bioactive molecules. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection during solid-phase peptide synthesis, facilitating the construction of complex peptide sequences with precision. Researchers appreciate its ability to improve the stability and solubility of peptides, which is crucial for pharmaceutical applications.

In addition to its role in peptide synthesis, Fmoc-L-cyclohexylglycine has shown promise in the development of novel therapeutics, particularly in the field of cancer research and drug delivery systems. Its unique structural properties enable the formation of stable secondary structures, which can enhance the biological activity of peptides. This compound is an essential tool for chemists and biochemists aiming to create innovative solutions in drug design and development, making it a valuable addition to any research laboratory.

Synonyms
Fmoc-L-Chg-OH, Fmoc-cyclohexyl-Gly-OH
CAS Number
161321-36-4
Purity
≥ 98% (HPLC)
Molecular Formula
C23H25NO4
Molecular Weight
379.4
MDL Number
MFCD00190878
Melting Point
180-184 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +6 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Chg-OH, Fmoc-cyclohexyl-Gly-OH
CAS Number
161321-36-4
Purity
≥ 98% (HPLC)
Molecular Formula
C23H25NO4
Molecular Weight
379.4
MDL Number
MFCD00190878
Melting Point
180-184 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +6 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-cyclohexylglycine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors, due to its ability to enhance the stability and bioavailability of peptide-based therapeutics.
  • Bioconjugation: Fmoc-L-cyclohexylglycine is used in bioconjugation processes, where it helps to attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Research in Neuroscience: This compound is valuable in neuroscience research, particularly in studying neuropeptides and their interactions, which can lead to insights into neurological disorders and potential treatments.
  • Custom Peptide Libraries: It is essential for creating custom peptide libraries for high-throughput screening, enabling researchers to discover new peptide functionalities and therapeutic candidates efficiently.

Citations