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Catalog Number:
02543
CAS Number:
81246-83-5
5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-guanosine
Purity:
≥ 99% (HPLC)
Synonym(s):
5'-O-DMT-NiBu-G
Documents
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-guanosine is a versatile nucleoside derivative that plays a crucial role in the synthesis of oligonucleotides and other nucleic acid-based products. This compound is particularly valued in molecular biology and biochemistry for its protective groups, which enhance the stability and efficiency of nucleic acid synthesis. Its unique structure allows for selective reactions, making it an essential building block in the development of therapeutic agents, diagnostic tools, and research applications.

Researchers and industry professionals utilize 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-guanosine in the production of modified RNA and DNA sequences, facilitating advancements in gene therapy and RNA interference technologies. Its ability to improve the solubility and bioavailability of nucleotides makes it a preferred choice in various applications, including drug development and genetic engineering. The compound's stability under various conditions further enhances its appeal, ensuring reliable performance in laboratory settings.

Synonyms
5'-O-DMT-NiBu-G
CAS Number
81246-83-5
Purity
≥ 99% (HPLC)
Molecular Formula
C35H37N5O8
Molecular Weight
655.72
MDL Number
MFCD00797504
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
5'-O-DMT-NiBu-G
CAS Number
81246-83-5
Purity
≥ 99% (HPLC)
Molecular Formula
C35H37N5O8
Molecular Weight
655.72
MDL Number
MFCD00797504
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-guanosine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, which are essential for various genetic research applications, including gene editing and molecular diagnostics.
  • Pharmaceutical Development: Its derivatives are explored in drug formulation, particularly in the development of antiviral medications targeting RNA viruses, enhancing therapeutic efficacy.
  • Biotechnology: Used in the production of RNA-based therapeutics, it plays a critical role in developing vaccines and treatments that utilize mRNA technology.
  • Research in Molecular Biology: This compound aids in the study of gene expression and regulation, providing insights into cellular processes and disease mechanisms.
  • Analytical Chemistry: It is employed as a standard in chromatography and mass spectrometry, facilitating the analysis of nucleic acids and their interactions.

Citations