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Catalog Number:
02491
Nα-Boc-Nim-2,4-dinitrophenyl-L-histidine 4-oxymethylphenylacetamidomethyl resin
Synonym(s):
Boc-L-His(Dnp)-PAM resin
Documents
$18.53 /1G
Pack Size Availability Price
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Product Information

Na-Boc-Nim-2,4-dinitrophenyl-L-histidine 4-oxymethylphenylacetamidomethyl is a versatile compound widely utilized in biochemical research and pharmaceutical applications. This derivative of histidine features a protective Boc (tert-butyloxycarbonyl) group, enhancing its stability and solubility, making it an excellent choice for peptide synthesis and drug development. Its unique structure allows for selective reactivity, which is crucial in the design of targeted therapies and in the study of protein interactions. Researchers often employ this compound in the synthesis of complex biomolecules, facilitating advancements in medicinal chemistry and the development of novel therapeutics.

The compound's dinitrophenyl group is particularly beneficial for applications in immunology and diagnostics, as it can serve as a hapten in antibody production. Additionally, its oxymethyl and acetamidomethyl functionalities provide further versatility, enabling modifications that can enhance biological activity or improve pharmacokinetic properties. With its broad range of applications, Na-Boc-Nim-2,4-dinitrophenyl-L-histidine 4-oxymethylphenylacetamidomethyl stands out as a valuable tool for researchers aiming to innovate in the fields of drug discovery and biochemical analysis.

Synonyms
Boc-L-His(Dnp)-PAM resin
MDL Number
MFCD00801362
Substitution
0.3-0.8 meq/g
Mesh Size
100-200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Boc-L-His(Dnp)-PAM resin
MDL Number
MFCD00801362
Substitution
0.3-0.8 meq/g
Mesh Size
100-200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-2,4-dinitrophenyl-L-histidine 4-oxymethylphenylacetamidomethyl is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in creating modified amino acids that enhance the stability and functionality of therapeutic peptides.
  • Drug Development: It plays a crucial role in the pharmaceutical industry, especially in the design of drug candidates that target specific biological pathways, aiding in the development of more effective treatments.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach drugs or imaging agents to biomolecules, improving the precision of drug delivery systems.
  • Diagnostics: In diagnostic applications, it can be employed in the development of assays that detect specific biomolecules, enhancing the sensitivity and specificity of diagnostic tests.
  • Research on Enzyme Inhibition: This chemical is valuable in studying enzyme inhibition mechanisms, providing insights that can lead to the development of novel inhibitors for therapeutic use.

Citations