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Catalog Number:
02480
CAS Number:
200623-62-7
Nα-Fmoc-Nδ-trityl-D-glutamine
Purity:
≥ 98.5% (HPLC)
Synonym(s):
Fmoc-D-Gln(Trt)-OH
Documents
$45.30 /1G
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Product Information

Na-Fmoc-Nd-trityl-D-glutamine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its trityl group enhances stability and solubility, making it an excellent choice for researchers focused on synthesizing complex peptides and proteins. The unique combination of these protective groups allows for efficient coupling reactions and minimizes side reactions, ensuring high yields and purity in the final products.

In the pharmaceutical industry, Na-Fmoc-Nd-trityl-D-glutamine is particularly valuable for developing peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its application extends to the fields of biochemistry and molecular biology, where it aids in the study of protein interactions and functions. Researchers appreciate its ability to facilitate the synthesis of modified peptides that can be used in drug discovery, vaccine development, and other innovative applications, making it a key component in advancing scientific research and therapeutic solutions.

Synonyms
Fmoc-D-Gln(Trt)-OH
CAS Number
200623-62-7
Purity
≥ 98.5% (HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.7
MDL Number
MFCD00151924
Melting Point
80 - 171 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 14.5 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Gln(Trt)-OH
CAS Number
200623-62-7
Purity
≥ 98.5% (HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.7
MDL Number
MFCD00151924
Melting Point
80 - 171 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 14.5 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nd-trityl-D-glutamine is widely utilized in research focused on

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and biologically relevant peptides.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, enhancing the efficacy and stability of therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of peptides to various biomolecules for targeted drug delivery systems.
  • Research in Neuroscience: It is valuable in neuroscience research for studying neuropeptides and their role in signaling pathways, contributing to advancements in understanding brain functions.
  • Protein Engineering: This chemical aids in protein engineering applications, allowing researchers to modify proteins for improved functionality or new properties, which is essential in biotechnology.

Citations