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Catalog Number:
02471
CAS Number:
84624-17-9
Fmoc-D-valine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Val-OH
Documents
$18.53 /1G
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Product Information

Fmoc-D-valine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an essential building block in the production of complex peptides and proteins. Researchers appreciate Fmoc-D-valine for its stability and ease of use in solid-phase peptide synthesis, enabling the creation of high-purity peptides that are vital for pharmaceutical applications and biochemical research.

In addition to its role in peptide synthesis, Fmoc-D-valine has potential applications in the development of therapeutics targeting various diseases, including cancer and metabolic disorders. Its ability to facilitate the incorporation of D-amino acids into peptides enhances the stability and bioactivity of the resulting compounds. This characteristic is particularly valuable in drug design, where modifications can lead to improved pharmacological properties. Overall, Fmoc-D-valine stands out as a critical reagent for researchers and industry professionals seeking to innovate in the fields of biochemistry and medicinal chemistry.

Synonyms
Fmoc-D-Val-OH
CAS Number
84624-17-9
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4
Molecular Weight
339.4
MDL Number
MFCD00062953
Melting Point
144 - 154 ?C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 17 ± 2 º (C = 1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Val-OH
CAS Number
84624-17-9
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4
Molecular Weight
339.4
MDL Number
MFCD00062953
Melting Point
144 - 154 ?C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 17 ± 2 º (C = 1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-valine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protecting group for amino acids in solid-phase peptide synthesis, allowing for the selective modification of peptide chains without unwanted reactions.
  • Drug Development: Its role in creating peptide-based therapeutics is crucial, particularly in designing drugs that target specific biological pathways, enhancing efficacy and reducing side effects.
  • Biotechnology: Fmoc-D-valine is used in the production of recombinant proteins, aiding in the development of enzymes and antibodies for various applications in diagnostics and therapeutics.
  • Research in Neuroscience: This compound is instrumental in synthesizing neuropeptides, which are vital for studying neural signaling and developing treatments for neurological disorders.
  • Custom Peptide Libraries: It enables the creation of diverse peptide libraries for high-throughput screening, facilitating the discovery of novel compounds with potential pharmaceutical applications.

Citations