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Catalog Number:
02458
CAS Number:
73731-37-0
Fmoc-L-threonine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-L-Thr-OH
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Product Information

Fmoc-L-threonine is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of threonine in solid-phase peptide synthesis. Its unique structure not only enhances the stability of the amino acid during synthesis but also allows for easy removal of the Fmoc group under mild conditions, making it an ideal choice for researchers focused on developing complex peptides and proteins.

In addition to its role in peptide synthesis, Fmoc-L-threonine is also valuable in the pharmaceutical and biotechnology industries, where it can be employed in the development of therapeutics and diagnostic tools. Its ability to incorporate into various peptide sequences enables the creation of bioactive compounds with enhanced properties. Researchers appreciate its high purity and reliability, which are crucial for successful experimental outcomes. Overall, Fmoc-L-threonine stands out as a key building block for innovative applications in life sciences.

Synonyms
Fmoc-L-Thr-OH
CAS Number
73731-37-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.4
MDL Number
MFCD00077072
PubChem ID
6992527
Melting Point
90 - 100 °C
Appearance
White powder
Optical Rotation
[a]D20 = -14 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Thr-OH
CAS Number
73731-37-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.4
MDL Number
MFCD00077072
PubChem ID
6992527
Melting Point
90 - 100 °C
Appearance
White powder
Optical Rotation
[a]D20 = -14 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-threonine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides. Its protective Fmoc group allows for selective deprotection, facilitating the incorporation of threonine into peptide chains, which is crucial for developing therapeutic peptides.
  • Biotechnology: In the field of biotechnology, Fmoc-L-threonine is used in the production of recombinant proteins. Its incorporation can enhance the stability and functionality of proteins, making it valuable for drug development and enzyme engineering.
  • Research in Drug Design: Researchers utilize this compound to study interactions between peptides and receptors. Its unique structure aids in understanding how modifications can influence biological activity, which is essential for designing new drugs.
  • Analytical Chemistry: Fmoc-L-threonine is employed in analytical methods such as chromatography. Its distinct properties help in the separation and identification of amino acids and peptides, improving the accuracy of analytical results.
  • Food Industry Applications: This compound is also explored for its potential in food science, particularly in the development of functional foods that may enhance nutritional profiles through the incorporation of specific amino acids.

Citations