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Catalog Number:
02450
CAS Number:
109074-94-4
Fmoc-L-proline N-hydroxysuccinimide ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Pro-OSu
Documents
$22.03 /1G
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Product Information

Fmoc-L-proline N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound serves as an essential building block in the formation of peptide bonds, particularly in the synthesis of peptides that require high purity and stability. Its unique structure, featuring the Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, allows for selective deprotection under mild conditions, making it an ideal choice for researchers focused on synthesizing complex peptides. Additionally, the N-hydroxysuccinimide moiety enhances the compound's reactivity, facilitating efficient coupling reactions with amino acids and other nucleophiles.

This compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where it is employed in the development of therapeutics and biologically active peptides. Its ability to streamline the synthesis process while maintaining high yields and purity makes it a preferred choice among professionals. Researchers can leverage Fmoc-L-proline N-hydroxysuccinimide ester to create a variety of peptide sequences, ultimately advancing their projects in drug discovery and development.

Synonyms
Fmoc-L-Pro-OSu
CAS Number
109074-94-4
Purity
≥ 99% (HPLC)
Molecular Formula
C24H22N2O6
Molecular Weight
434.45
MDL Number
MFCD00065673
Melting Point
161-166 °C
Appearance
White to off-white powder
Optical Rotation
[α]D20 = -59 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Pro-OSu
CAS Number
109074-94-4
Purity
≥ 99% (HPLC)
Molecular Formula
C24H22N2O6
Molecular Weight
434.45
MDL Number
MFCD00065673
Melting Point
161-166 °C
Appearance
White to off-white powder
Optical Rotation
[α]D20 = -59 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-proline N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of proline residues, which are crucial for protein structure and function.
  • Drug Development: It is employed in the pharmaceutical industry to create peptide-based drugs, enhancing the efficacy and stability of therapeutic agents.
  • Bioconjugation: The compound facilitates the conjugation of peptides to various biomolecules, which is essential in developing targeted drug delivery systems and diagnostic tools.
  • Research in Biochemistry: It is used in various biochemical studies to investigate protein interactions and folding, providing insights into cellular processes.
  • Custom Peptide Libraries: Researchers utilize this ester to generate diverse peptide libraries for screening potential drug candidates, accelerating the discovery process.

Citations