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Catalog Number:
02447
CAS Number:
95753-55-2
Fmoc-4-nitro-L-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Phe(4-NO2)-OH, Fmoc-p-nitro-L-Phe-OH, Fmoc-p-nitro-L-Phe-OH
Documents
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Product Information

Fmoc-4-nitro-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. The presence of the nitro group on the phenyl ring enhances its reactivity, making it an excellent choice for researchers looking to incorporate specific functionalities into their peptide sequences. Its unique structure allows for efficient coupling reactions, facilitating the formation of complex peptides with desired biological activities.

In the pharmaceutical industry, Fmoc-4-nitro-L-phenylalanine serves as a building block for the synthesis of bioactive peptides, which can be used in therapeutic applications, including cancer treatment and antimicrobial agents. Researchers appreciate its stability under various conditions, which ensures reliable performance in laboratory settings. Additionally, its compatibility with automated peptide synthesizers streamlines the production process, making it an essential tool for both academic and industrial applications. With its robust properties and practical uses, Fmoc-4-nitro-L-phenylalanine stands out as a valuable asset for professionals in the field.

Synonyms
Fmoc-L-Phe(4-NO2)-OH, Fmoc-p-nitro-L-Phe-OH, Fmoc-p-nitro-L-Phe-OH
CAS Number
95753-55-2
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD00057810
PubChem ID
7016054
Melting Point
179 - 181 °C
Appearance
White to off-white solid
Optical Rotation
179 - 181 °C
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(4-NO2)-OH, Fmoc-p-nitro-L-Phe-OH, Fmoc-p-nitro-L-Phe-OH
CAS Number
95753-55-2
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD00057810
PubChem ID
7016054
Melting Point
179 - 181 °C
Appearance
White to off-white solid
Optical Rotation
179 - 181 °C
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-nitro-L-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences for various applications in biochemistry and pharmacology.
  • Drug Development: Its unique properties make it valuable in the development of novel therapeutic agents, particularly in targeting specific biological pathways, enhancing drug efficacy.
  • Bioconjugation: Fmoc-4-nitro-L-phenylalanine can be used in bioconjugation processes, facilitating the attachment of biomolecules to drugs or imaging agents for improved delivery and targeting in medical applications.
  • Fluorescent Probes: Researchers utilize this compound to develop fluorescent probes for studying protein interactions and cellular processes, providing insights into complex biological systems.
  • Research in Cancer Therapeutics: Its application in cancer research is notable, as it aids in the design of peptide-based inhibitors that can selectively target cancer cells, potentially leading to more effective treatments.

Citations