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Catalog Number:
02444
CAS Number:
86123-10-6
Fmoc-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Phe-OH
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Product Information

Fmoc-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Researchers and industry professionals appreciate its ability to facilitate the formation of complex peptides while minimizing side reactions, thus ensuring high purity and yield. Fmoc-D-phenylalanine is particularly valuable in the pharmaceutical sector for developing peptide-based therapeutics, including those targeting cancer and metabolic disorders. Its unique properties allow for straightforward deprotection under mild conditions, enabling efficient workflow in laboratory settings.

In addition to its applications in peptide synthesis, Fmoc-D-phenylalanine serves as a building block in the design of novel biomaterials and drug delivery systems. Its hydrophobic nature and structural characteristics make it suitable for creating self-assembling nanostructures, which can enhance the bioavailability of therapeutic agents. With its proven track record in research and industry, Fmoc-D-phenylalanine stands out as a crucial component for advancing peptide chemistry and developing innovative solutions in biomedicine.

Synonyms
Fmoc-D-Phe-OH
CAS Number
86123-10-6
Purity
≥ 98% (HPLC)
Molecular Formula
C24H21NO4
Molecular Weight
387.4
MDL Number
MFCD00062955
PubChem ID
7221556
Melting Point
180 - 195 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]20D = 37 ± 2.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe-OH
CAS Number
86123-10-6
Purity
≥ 98% (HPLC)
Molecular Formula
C24H21NO4
Molecular Weight
387.4
MDL Number
MFCD00062955
PubChem ID
7221556
Melting Point
180 - 195 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]20D = 37 ± 2.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids during the formation of peptides.
  • Drug Development: It is used in the design of peptide-based drugs, enhancing the stability and bioavailability of therapeutic agents in pharmaceutical formulations.
  • Biotechnology: Researchers employ it in the creation of peptide libraries for screening potential drug candidates, facilitating the discovery of new therapeutic compounds.
  • Protein Engineering: Fmoc-D-phenylalanine is instrumental in modifying proteins to improve their function or stability, which is crucial in developing biocatalysts and enzymes.
  • Research in Neuroscience: This compound is utilized in studies related to neurotransmitter pathways, helping to understand the role of peptides in brain function and behavior.

Citations