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Catalog Number:
02439
CAS Number:
112913-64-1
Fmoc-L-methionine N-hydroxysuccinimide ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Met-OSu
Documents
$29.34 /1G
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Product Information

Fmoc-L-methionine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound serves as a valuable building block in the production of peptides, particularly in solid-phase peptide synthesis, where its protective Fmoc (fluorenylmethyloxycarbonyl) group allows for selective deprotection and subsequent coupling reactions. Its N-hydroxysuccinimide ester functionality enhances the reactivity towards amines, making it an excellent choice for conjugating peptides to various biomolecules, including proteins and antibodies.

Researchers and industry professionals appreciate Fmoc-L-methionine N-hydroxysuccinimide ester for its ability to facilitate the formation of stable amide bonds, which are crucial in the development of therapeutic peptides and drug delivery systems. Its unique properties allow for efficient coupling reactions, leading to high yields and purity of the final products. This compound is particularly beneficial in the fields of drug discovery, vaccine development, and the creation of targeted therapies, where precise control over peptide structure and function is essential.

Synonyms
Fmoc-L-Met-OSu
CAS Number
112913-64-1
Purity
≥ 99% (HPLC)
Molecular Formula
C24H24N2O6S
Molecular Weight
468.6
MDL Number
MFCD00065666
Melting Point
129-139 °C
Appearance
White powder
Optical Rotation
[a]D20
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Met-OSu
CAS Number
112913-64-1
Purity
≥ 99% (HPLC)
Molecular Formula
C24H24N2O6S
Molecular Weight
468.6
MDL Number
MFCD00065666
Melting Point
129-139 °C
Appearance
White powder
Optical Rotation
[a]D20
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-methionine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It is used in the development of peptide-based therapeutics, offering a stable and effective means to modify drug properties for enhanced efficacy.
  • Bioconjugation: The compound facilitates the conjugation of peptides to various biomolecules, which is essential in creating targeted drug delivery systems.
  • Protein Engineering: Researchers employ it to introduce specific modifications in proteins, improving their stability and functionality in various applications.
  • Diagnostic Applications: It is utilized in the development of peptide-based diagnostics, enhancing the sensitivity and specificity of detection methods in clinical settings.

Citations