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Catalog Number:
02434
CAS Number:
110990-07-3
Nα-Fmoc-Nε-Z-D-lysine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Lys(Z)-OH
Documents
$22.03 /1G
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Product Information

Na-Fmoc-Ne-Z-D-lysine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is crucial for the selective protection of the amino group during the synthesis of complex peptides. Its unique structure allows for enhanced stability and solubility, making it an ideal choice for researchers working in the fields of medicinal chemistry and biochemistry.

In practical applications, Na-Fmoc-Ne-Z-D-lysine is particularly valuable in the synthesis of peptide-based therapeutics and in the development of novel drug candidates. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of the amino acid chain positions it as a key player in the production of biologically active compounds. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis, leading to higher yields and purities in their final products.

Synonyms
Fmoc-D-Lys(Z)-OH
CAS Number
110990-07-3
Purity
≥ 98% (HPLC)
Molecular Formula
C29H30N2O6
Molecular Weight
502.6
MDL Number
MFCD00065663
Melting Point
114 - 116 ºC
Appearance
White to off-white powder
Optical Rotation
[a]20D = +11 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Lys(Z)-OH
CAS Number
110990-07-3
Purity
≥ 98% (HPLC)
Molecular Formula
C29H30N2O6
Molecular Weight
502.6
MDL Number
MFCD00065663
Melting Point
114 - 116 ºC
Appearance
White to off-white powder
Optical Rotation
[a]20D = +11 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-Z-D-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development.
  • Bioconjugation: Its unique protective group facilitates the conjugation of peptides to other molecules, enhancing the delivery and efficacy of therapeutic agents in pharmaceutical applications.
  • Protein Engineering: Used in the modification of proteins, it helps in studying protein interactions and functions, which is crucial for understanding biological processes.
  • Drug Design: The compound's structure allows for the design of novel drugs that can target specific biological pathways, providing an advantage in developing more effective treatments.
  • Research in Cancer Therapy: It is employed in the development of targeted therapies, where its ability to modify peptides can lead to more precise treatments with fewer side effects.

Citations