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Catalog Number:
02427
CAS Number:
114360-54-2
Fmoc-D-leucine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Leu-OH, (R)-Fmoc-2-amino-4-methylpentanoic acid
Documents
$20.20 /1G
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Product Information

Fmoc-D-leucine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for easy cleavage of the Fmoc group under mild basic conditions, making it an ideal choice for solid-phase peptide synthesis (SPPS). Researchers appreciate Fmoc-D-leucine for its ability to enhance the stability and solubility of peptides, facilitating the development of complex biomolecules for therapeutic applications.

In addition to its role in peptide synthesis, Fmoc-D-leucine is also employed in the production of various bioactive compounds and can be used in the design of drug candidates targeting specific biological pathways. Its application extends to the fields of biochemistry, molecular biology, and medicinal chemistry, where it aids in the exploration of new therapeutic strategies. With its reliable performance and compatibility with various synthetic methodologies, Fmoc-D-leucine stands out as a valuable tool for researchers and industry professionals alike.

Synonyms
Fmoc-D-Leu-OH, (R)-Fmoc-2-amino-4-methylpentanoic acid
CAS Number
114360-54-2
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.4
MDL Number
MFCD00062957
Melting Point
153 - 160 °C
Appearance
White powder
Optical Rotation
[a]D20 = 25 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Leu-OH, (R)-Fmoc-2-amino-4-methylpentanoic acid
CAS Number
114360-54-2
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.4
MDL Number
MFCD00062957
Melting Point
153 - 160 °C
Appearance
White powder
Optical Rotation
[a]D20 = 25 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-leucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, allowing researchers to create specific sequences for therapeutic applications.
  • Drug Development: Its role in drug design is crucial, particularly in developing peptide-based drugs that target specific biological pathways, enhancing efficacy and reducing side effects.
  • Biotechnology: In the field of biotechnology, Fmoc-D-leucine is employed in the production of recombinant proteins, aiding in the development of vaccines and enzymes.
  • Research in Neuroscience: This compound is used in studies exploring neurotransmitter interactions, contributing to advancements in understanding neurological disorders.
  • Custom Synthesis Services: Many laboratories offer custom synthesis of Fmoc-D-leucine derivatives, providing tailored solutions for specific research needs and enhancing experimental flexibility.

Citations