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Catalog Number:
02411
CAS Number:
132327-80-1
Nα-Fmoc- Nδ-trityl-L-glutamine
Purity:
≥ 99.7% (Chiral HPLC)
Synonym(s):
Fmoc-L-Gln(Trt)-OH
Documents
$18.53 /1G
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Product Information

Na-Fmoc- Nd-trityl-L-glutamine is a highly versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of the amine group during the synthesis of peptides. The trityl group further enhances its stability and solubility, making it an ideal choice for researchers engaged in the synthesis of complex peptides and proteins. Its unique structure allows for efficient coupling reactions, facilitating the formation of peptide bonds while minimizing side reactions.

This compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where it is utilized in the development of therapeutic peptides and biologically active compounds. Researchers appreciate its ability to improve the yield and purity of synthesized peptides, making it a preferred choice in laboratories focused on drug discovery and development. With its robust performance and reliability, Na-Fmoc- Nd-trityl-L-glutamine stands out as a key reagent for professionals aiming to advance their research in peptide chemistry.

Synonyms
Fmoc-L-Gln(Trt)-OH
CAS Number
132327-80-1
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.7
MDL Number
MFCD00077056
PubChem ID
2801740
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Gln(Trt)-OH
CAS Number
132327-80-1
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.7
MDL Number
MFCD00077056
PubChem ID
2801740
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc- Nd-trityl-L-glutamine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of specific amino acids in a controlled manner, which is essential for developing therapeutic peptides.
  • Drug Development: It plays a significant role in the pharmaceutical industry for creating novel drug candidates, particularly in the design of peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: Researchers use this compound to facilitate bioconjugation processes, linking peptides to other biomolecules, which enhances the efficacy of drugs and diagnostic agents.
  • Protein Engineering: It is employed in protein engineering applications, where modifications to amino acid sequences are necessary to improve protein stability and functionality.
  • Research in Neuroscience: The compound is utilized in studies related to neurotransmitter functions, helping researchers understand the role of specific peptides in neurological processes.

Citations