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Catalog Number:
02409
CAS Number:
113534-17-1
Nα-Fmoc-Nδ-4,4'-dimethoxybenzhydryl-L-glutamine
Purity:
≥ 98% (TLC)
Synonym(s):
Fmoc-L-Gln(Mbh)-OH
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Product Information

Na-Fmoc-Nd-4,4'-dimethoxybenzhydryl-L-glutamine is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its structure includes a dimethoxybenzhydryl moiety, enhancing its stability and solubility in organic solvents, making it an excellent choice for researchers engaged in complex peptide synthesis.

This compound is particularly beneficial in the pharmaceutical industry for the development of peptide-based therapeutics, where precision in amino acid sequence is crucial. Its unique properties allow for efficient coupling reactions and improved yields in peptide formation, which are vital for producing high-quality peptides for research and therapeutic applications. Additionally, Na-Fmoc-Nd-4,4'-dimethoxybenzhydryl-L-glutamine's compatibility with various coupling reagents makes it a versatile tool in the synthesis of bioactive peptides, providing researchers with a reliable option for their synthetic needs.

Synonyms
Fmoc-L-Gln(Mbh)-OH
CAS Number
113534-17-1
Purity
≥ 98% (TLC)
Molecular Formula
C35H34N2O7
Molecular Weight
594.7
MDL Number
MFCD00065644
PubChem ID
4349446
Appearance
White powder
Optical Rotation
[a]D24 = -6 ± 1° (C=1 in dimethylformamide)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Gln(Mbh)-OH
CAS Number
113534-17-1
Purity
≥ 98% (TLC)
Molecular Formula
C35H34N2O7
Molecular Weight
594.7
MDL Number
MFCD00065644
PubChem ID
4349446
Appearance
White powder
Optical Rotation
[a]D24 = -6 ± 1° (C=1 in dimethylformamide)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nd-4,4'-dimethoxybenzhydryl-L-glutamine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for researchers in medicinal chemistry.
  • Drug Development: The compound plays a crucial role in the design of new pharmaceuticals, particularly in the development of peptide-based drugs. Its ability to enhance the solubility and bioavailability of drug candidates is a significant advantage.
  • Bioconjugation: It is used in bioconjugation processes to attach biomolecules to surfaces or other molecules. This application is vital in creating targeted drug delivery systems and improving therapeutic efficacy.
  • Research in Neurobiology: The compound is utilized in studies related to neuropeptides, aiding in the understanding of neurological pathways and potential treatments for neurodegenerative diseases.
  • Analytical Chemistry: It is employed in analytical techniques such as chromatography and mass spectrometry, helping researchers to identify and quantify peptides in complex mixtures.

Citations