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Catalog Number:
02399
CAS Number:
136050-67-4
Fmoc-S-4-methylbenzyl-L-cysteine
Purity:
≥ 98%
Synonym(s):
Fmoc-L-Cys(pMeBzl)-OH
Documents
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Product Information

Fmoc-S-4-methylbenzyl-L-cysteine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its unique structure, characterized by the incorporation of a 4-methylbenzyl group, enhances its stability and solubility, making it an ideal choice for researchers focusing on the development of peptide-based therapeutics.

In the pharmaceutical industry, Fmoc-S-4-methylbenzyl-L-cysteine is particularly valuable for the synthesis of bioactive peptides, which can serve as potential drug candidates for various diseases. Its application extends to the fields of biochemistry and molecular biology, where it aids in the study of protein interactions and functions. Researchers appreciate its ability to facilitate the formation of disulfide bonds, which are crucial for the structural integrity of many proteins. Overall, this compound stands out for its efficiency and reliability in peptide synthesis, making it a preferred choice for professionals seeking high-quality reagents.

Synonyms
Fmoc-L-Cys(pMeBzl)-OH
CAS Number
136050-67-4
Purity
≥ 98%
Molecular Formula
C26H25NO4S
Molecular Weight
447.6
MDL Number
MFCD00065634
Melting Point
151-157º C
Optical Rotation
á25D = -29.2º ± 0.5º (c=1% in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Cys(pMeBzl)-OH
CAS Number
136050-67-4
Purity
≥ 98%
Molecular Formula
C26H25NO4S
Molecular Weight
447.6
MDL Number
MFCD00065634
Melting Point
151-157º C
Optical Rotation
á25D = -29.2º ± 0.5º (c=1% in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-4-methylbenzyl-L-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling researchers to create complex and functional peptide sequences efficiently.
  • Drug Development: Its unique structure allows for the incorporation of sulfur-containing amino acids in drug candidates, which can enhance the pharmacological properties and bioavailability of therapeutic agents.
  • Bioconjugation: The compound is useful in bioconjugation processes, where it can be attached to various biomolecules, aiding in the development of targeted drug delivery systems and diagnostic tools.
  • Research in Protein Engineering: Fmoc-S-4-methylbenzyl-L-cysteine is employed in protein engineering to introduce specific functionalities, making it valuable for creating proteins with tailored properties for industrial and therapeutic applications.
  • Analytical Chemistry: This chemical can be used in analytical methods to study protein interactions and stability, providing insights into biochemical pathways and potential therapeutic targets.

Citations