Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02394
CAS Number:
78553-23-8
Fmoc-L-aspartic acid β-tert-butyl ester α-N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Asp(OtBu)-OSu
Documents
$50.00 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc group that facilitates the selective coupling of amino acids, making it an essential building block in the synthesis of peptides and proteins. Its unique structure allows for efficient conjugation reactions, particularly in the formation of peptide-based therapeutics and bioconjugates. Researchers appreciate its stability under various conditions, which enhances its applicability in both academic and industrial settings.

In addition to its role in peptide synthesis, this compound is also valuable in the development of targeted drug delivery systems. The N-hydroxysuccinimide ester functionality enables the formation of stable amide bonds with primary amines, allowing for the creation of complex biomolecules. This characteristic is particularly beneficial in the design of drug carriers and diagnostic agents, where precise targeting and controlled release are crucial. Overall, Fmoc-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester stands out for its efficiency and versatility in various biochemical applications.

Synonyms
Fmoc-L-Asp(OtBu)-OSu
CAS Number
78553-23-8
Purity
≥ 98% (HPLC)
Molecular Formula
C27H28N2O8
Molecular Weight
508.5
MDL Number
MFCD00057809
Melting Point
126 - 133 °C
Appearance
White powder
Optical Rotation
[a]D20 = -30 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asp(OtBu)-OSu
CAS Number
78553-23-8
Purity
≥ 98% (HPLC)
Molecular Formula
C27H28N2O8
Molecular Weight
508.5
MDL Number
MFCD00057809
Melting Point
126 - 133 °C
Appearance
White powder
Optical Rotation
[a]D20 = -30 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling researchers to create complex peptide sequences efficiently.
  • Drug Development: It is used in the development of peptide-based drugs, allowing for the modification of peptide structures to enhance stability and bioactivity, which is crucial in pharmaceutical research.
  • Bioconjugation: The compound facilitates the conjugation of peptides to various biomolecules, such as antibodies or drugs, improving targeted delivery systems in therapeutic applications.
  • Research in Neuroscience: It is applied in studies related to neurotransmitter signaling, particularly in the synthesis of aspartic acid derivatives, which are important in understanding synaptic transmission.
  • Protein Engineering: This chemical is utilized in modifying proteins to study their function and interactions, providing insights into protein behavior and potential applications in biotechnology.

Citations