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Catalog Number:
02386
CAS Number:
132388-59-1
Nα-Fmoc-Nγ-trityl-L-asparagine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Fmoc-L-Asn(Trt)-OH
Documents
$20.20 /5G
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Product Information

Na-Fmoc-Ng-trityl-L-asparagine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis, making it an essential building block for researchers in the field of biochemistry and pharmaceuticals. Its trityl protection on the nitrogen atom enhances stability and solubility, allowing for efficient purification and manipulation in various chemical environments.

Researchers and industry professionals appreciate Na-Fmoc-Ng-trityl-L-asparagine for its ability to streamline the synthesis of complex peptides, particularly those involved in therapeutic applications. Its unique properties enable the formation of high-purity peptides, which are crucial for developing biologically active compounds. This compound is particularly beneficial in the synthesis of peptide-based drugs, where precision and efficiency are paramount. With its robust performance in peptide synthesis, Na-Fmoc-Ng-trityl-L-asparagine stands out as a reliable choice for advancing research and development in the pharmaceutical industry.

Synonyms
Fmoc-L-Asn(Trt)-OH
CAS Number
132388-59-1
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C38H32N2O5
Molecular Weight
596.7
MDL Number
MFCD00077049
PubChem ID
3536635
Melting Point
200 - 220 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -14.5 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asn(Trt)-OH
CAS Number
132388-59-1
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C38H32N2O5
Molecular Weight
596.7
MDL Number
MFCD00077049
PubChem ID
3536635
Melting Point
200 - 220 °C (Lit.)
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -14.5 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ng-trityl-L-asparagine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex proteins with specific functionalities.
  • Drug Development: It plays a significant role in pharmaceutical research, particularly in the development of peptide-based drugs, which can offer targeted therapeutic effects with fewer side effects compared to traditional small-molecule drugs.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps in attaching biomolecules to surfaces or other molecules, enhancing the efficacy of diagnostics and therapeutics in the biomedical field.
  • Research in Neuroscience: Its application in the synthesis of neuropeptides aids researchers in studying neurological pathways and developing treatments for neurodegenerative diseases.
  • Protein Engineering: This chemical is instrumental in protein engineering, allowing scientists to modify proteins for improved stability and activity, which is crucial in both industrial applications and therapeutic development.

Citations