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Catalog Number:
02377
CAS Number:
120075-24-3
Nα-Fmoc-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Arg(Mtr)-OH
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Product Information

Na-Fmoc-Nw-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine is a versatile and highly functionalized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to enhance the stability and solubility of peptides, making it an ideal choice for researchers focused on developing therapeutic agents. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group and a sulfonyl moiety, allows for selective reactions and modifications, facilitating the synthesis of complex peptide sequences.

In practical applications, Na-Fmoc-Nw-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine is commonly employed in solid-phase peptide synthesis (SPPS), where it serves as a building block for the creation of bioactive peptides. Its ability to improve the pharmacokinetic properties of peptides makes it particularly advantageous in the design of peptide-based drugs. Researchers in pharmaceutical and biotechnological industries will find this compound invaluable for developing novel therapeutics with enhanced efficacy and reduced side effects.

Synonyms
Fmoc-D-Arg(Mtr)-OH
CAS Number
120075-24-3
Purity
≥ 99% (HPLC)
Molecular Formula
C31H36N4O7S
Molecular Weight
608.9
MDL Number
MFCD00065616
Melting Point
123-130º C
Optical Rotation
á20D = +5.5 ± 1º
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Arg(Mtr)-OH
CAS Number
120075-24-3
Purity
≥ 99% (HPLC)
Molecular Formula
C31H36N4O7S
Molecular Weight
608.9
MDL Number
MFCD00065616
Melting Point
123-130º C
Optical Rotation
á20D = +5.5 ± 1º
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nw-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without disrupting the overall structure. This is crucial for researchers developing new therapeutic peptides.
  • Drug Development: Its unique chemical properties make it valuable in the pharmaceutical industry for designing and optimizing drug candidates, particularly those targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Diagnostics: In the field of diagnostics, this chemical can be employed in the development of assays and tests, improving the sensitivity and specificity of detection methods.
  • Research on Protein Interactions: It aids in studying protein-protein interactions, providing insights into cellular mechanisms and potential therapeutic targets, which is essential for advancing biomedical research.

Citations