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Catalog Number:
02375
CAS Number:
135673-97-1
Fmoc-β-cyclohexyl-L-alanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Cha-OH, Fmoc-3-cyclohexyl-L-alanine, (S-N-Fmoc-amino-2-cyclohexyl-propanoic acid
Documents
$43.87 /1G
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Product Information

Fmoc-b-cyclohexyl-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a cyclohexyl side chain, which enhances the hydrophobic interactions in peptides, making it particularly valuable for researchers focusing on the design of bioactive compounds. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. Its unique structure not only aids in improving the solubility and stability of peptides but also facilitates the development of novel therapeutics with enhanced efficacy.

In practical applications, Fmoc-b-cyclohexyl-L-alanine is commonly employed in the synthesis of cyclic peptides and peptidomimetics, which are crucial in drug discovery and development. Researchers appreciate its ability to create conformationally constrained structures that can lead to improved binding affinities and selectivity in biological systems. This compound stands out among similar derivatives due to its favorable properties, making it an essential choice for professionals in pharmaceutical and biochemical research.

Synonyms
Fmoc-L-Cha-OH, Fmoc-3-cyclohexyl-L-alanine, (S-N-Fmoc-amino-2-cyclohexyl-propanoic acid
CAS Number
135673-97-1
Purity
≥ 99% (HPLC)
Molecular Formula
C24H27NO4
Molecular Weight
393.5
MDL Number
MFCD00065614
Melting Point
126-132º C
Optical Rotation
á20D = -24.0 ± 2º (c = 1, DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Cha-OH, Fmoc-3-cyclohexyl-L-alanine, (S-N-Fmoc-amino-2-cyclohexyl-propanoic acid
CAS Number
135673-97-1
Purity
≥ 99% (HPLC)
Molecular Formula
C24H27NO4
Molecular Weight
393.5
MDL Number
MFCD00065614
Melting Point
126-132º C
Optical Rotation
á20D = -24.0 ± 2º (c = 1, DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-b-cyclohexyl-L-alanine is widely utilized in research focused on

  • Peptide Synthesis: This compound is commonly used as a building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, particularly in targeting specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The Fmoc group enables easy attachment to various biomolecules, facilitating the development of bioconjugates for targeted drug delivery systems.
  • Research in Neuroscience: This compound is utilized in studies related to neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.
  • Custom Peptide Libraries: It serves as a key component in creating diverse peptide libraries for high-throughput screening, aiding in the discovery of new bioactive compounds.

Citations