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Catalog Number:
02369
CAS Number:
35661-39-3
Fmoc-L-alanine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Fmoc-L-Ala-OH
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Product Information

Fmoc-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and organic chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its stability under various reaction conditions makes it an ideal choice for researchers looking to construct complex peptide sequences. Fmoc-L-alanine is particularly valued in the pharmaceutical industry for its role in developing peptide-based therapeutics and in the production of custom peptides for research applications.

The unique properties of Fmoc-L-alanine allow for efficient coupling reactions, facilitating the formation of peptide bonds while minimizing side reactions. Its compatibility with solid-phase peptide synthesis (SPPS) techniques further enhances its appeal, enabling streamlined workflows in peptide production. Researchers and industry professionals can leverage Fmoc-L-alanine to create a diverse range of peptides, including those used in drug development, diagnostics, and bioconjugation applications. This compound stands out for its ease of use and effectiveness in producing high-purity peptides, making it a preferred choice in laboratories and manufacturing settings.

Synonyms
Fmoc-L-Ala-OH
CAS Number
35661-39-3
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C18H17NO4
Molecular Weight
311.3
MDL Number
MFCD00037139
PubChem ID
100108
Melting Point
147 - 157 °C (Lit.)
Appearance
White to off-white powder or crystalline powder
Optical Rotation
[a]D20 = -18 ± 2.5 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Ala-OH
CAS Number
35661-39-3
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C18H17NO4
Molecular Weight
311.3
MDL Number
MFCD00037139
PubChem ID
100108
Melting Point
147 - 157 °C (Lit.)
Appearance
White to off-white powder or crystalline powder
Optical Rotation
[a]D20 = -18 ± 2.5 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-alanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting the overall structure of the peptide.
  • Drug Development: Researchers use Fmoc-L-alanine in the design of peptide-based drugs, taking advantage of its stability and compatibility with various coupling reactions.
  • Biotechnology: In the field of biotechnology, it is applied in the production of recombinant proteins, enhancing the efficiency of protein expression systems.
  • Analytical Chemistry: This chemical is employed in various analytical techniques, such as HPLC, to separate and identify amino acids and peptides, aiding in quality control processes.
  • Education and Training: Fmoc-L-alanine is commonly used in academic laboratories for teaching purposes, providing students with hands-on experience in peptide chemistry and synthesis techniques.

Citations