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Catalog Number:
02357
CAS Number:
105832-38-0
2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate
Purity:
≥ 99% (HPLC)
Synonym(s):
TSTU, N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uroniumtetrafluoroborate
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Product Information

2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate is a versatile coupling reagent widely utilized in peptide synthesis and organic chemistry. This compound is particularly valued for its ability to activate carboxylic acids, facilitating the formation of amide bonds with high efficiency. Its unique structure allows for a more stable intermediate, which can lead to improved yields and reduced side reactions compared to traditional coupling agents. Researchers and industry professionals appreciate its effectiveness in various applications, including drug development and the synthesis of complex biomolecules.

In addition to its role in peptide synthesis, 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate is also employed in the modification of proteins and other macromolecules, enhancing their functionality for therapeutic and diagnostic purposes. Its compatibility with a wide range of solvents and reaction conditions makes it an ideal choice for both laboratory and industrial applications. The compound's high purity and stability further contribute to its appeal, ensuring reliable performance in demanding chemical processes.

Synonyms
TSTU, N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uroniumtetrafluoroborate
CAS Number
105832-38-0
Purity
≥ 99% (HPLC)
Molecular Formula
C9H16O3N3BF4
Molecular Weight
301.1
MDL Number
MFCD00077875
Melting Point
196 - 205 °C
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
TSTU, N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uroniumtetrafluoroborate
CAS Number
105832-38-0
Purity
≥ 99% (HPLC)
Molecular Formula
C9H16O3N3BF4
Molecular Weight
301.1
MDL Number
MFCD00077875
Melting Point
196 - 205 °C
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a coupling reagent in peptide synthesis, facilitating the formation of peptide bonds efficiently. Its ability to activate carboxylic acids makes it a preferred choice for researchers in biochemistry and pharmaceutical development.
  • Protein Modification: It is used to modify proteins for various applications, including drug delivery systems. By enhancing the stability and solubility of proteins, it aids in the development of more effective therapeutic agents.
  • Bioconjugation: The compound plays a crucial role in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules. This is particularly beneficial in the fields of diagnostics and targeted drug delivery.
  • Organic Synthesis: In organic chemistry, it is employed as a reagent for the synthesis of complex molecules, providing a versatile tool for chemists looking to create novel compounds with specific properties.
  • Research in Material Science: It is also explored in material science for developing new polymers and materials with enhanced properties, contributing to advancements in various industrial applications.

Citations