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Catalog Number:
02320
CAS Number:
772-33-8
2-Hydroxy-5-nitrobenzyl bromide
Purity:
≥ 97% (GC)
Synonym(s):
α-Bromo-4-nitro-2-cresol, Koshland's Reagent I
Hazmat
Documents
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Product Information

2-Hydroxy-5-nitrobenzyl bromide is a versatile chemical compound recognized for its significant applications in organic synthesis and pharmaceutical development. This compound, also known as 2-(bromomethyl)-4-nitrophenol, features a unique structure that allows it to act as a key intermediate in the synthesis of various biologically active molecules. Its bromomethyl and nitro functionalities make it particularly useful in nucleophilic substitution reactions, enabling the introduction of diverse functional groups into target molecules.

Researchers and industry professionals utilize 2-Hydroxy-5-nitrobenzyl bromide in the development of pharmaceuticals, agrochemicals, and dyes, where it serves as a building block for more complex compounds. Its ability to facilitate the formation of carbon-carbon and carbon-heteroatom bonds enhances its utility in medicinal chemistry, particularly in the design of novel therapeutic agents. The compound's stability and reactivity profile make it an attractive choice for those looking to streamline their synthetic pathways while achieving high yields.

Synonyms
α-Bromo-4-nitro-2-cresol, Koshland's Reagent I
CAS Number
772-33-8
Purity
≥ 97% (GC)
Molecular Formula
C7H6BrNO3
Molecular Weight
232.04
MDL Number
MFCD00007340
PubChem ID
13044
Melting Point
145-151? C
Appearance
Beige to pale yellow powder
Conditions
Store at RT
General Information
Synonyms
α-Bromo-4-nitro-2-cresol, Koshland's Reagent I
CAS Number
772-33-8
Purity
≥ 97% (GC)
Molecular Formula
C7H6BrNO3
Molecular Weight
232.04
MDL Number
MFCD00007340
PubChem ID
13044
Melting Point
145-151? C
Appearance
Beige to pale yellow powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Hydroxy-5-nitrobenzyl bromide is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as an important intermediate in the synthesis of various pharmaceutical agents, particularly in the development of anti-inflammatory and analgesic drugs.
  • Organic Synthesis: It is commonly used in organic chemistry for the preparation of complex molecules, enabling researchers to create new compounds with desired properties.
  • Bioconjugation: The bromide group allows for efficient bioconjugation reactions, making it valuable in the development of targeted drug delivery systems and diagnostic agents.
  • Material Science: In material science, it can be used to modify polymer surfaces, enhancing their properties for applications in coatings and adhesives.
  • Research in Environmental Chemistry: This compound is also studied for its potential applications in environmental remediation, particularly in the degradation of pollutants.

Citations