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Catalog Number:
02286
CAS Number:
870-46-2
Boc-hydrazide
Purity:
≥ 99% (Assay)
Synonym(s):
tert-Butyl carbazate, Carbonic acid tert-butyl ester hydrazide
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Product Information

Boc-hydrazide is a versatile chemical compound widely utilized in organic synthesis and pharmaceutical research. Its unique structure, featuring a tert-butyl group, enhances its stability and solubility, making it an ideal candidate for various applications. This compound is particularly valuable in the synthesis of hydrazones and other nitrogen-containing heterocycles, which are essential in the development of agrochemicals and pharmaceuticals. Researchers appreciate Boc-hydrazide for its ability to facilitate the formation of peptide bonds, thereby playing a crucial role in peptide synthesis and drug development.

Additionally, Boc-hydrazide serves as a protecting group in organic reactions, allowing for selective functionalization of other reactive sites. Its ease of removal under mild conditions makes it a preferred choice among chemists. With its broad applicability in medicinal chemistry, including the design of inhibitors and other bioactive compounds, Boc-hydrazide stands out as a key reagent in the toolkit of researchers and industry professionals alike.

Synonyms
tert-Butyl carbazate, Carbonic acid tert-butyl ester hydrazide
CAS Number
870-46-2
Purity
≥ 99% (Assay)
Molecular Formula
C5H12N2O2
Molecular Weight
132.2
MDL Number
MFCD00007593
PubChem ID
70091
Melting Point
35 - 44 °C
Appearance
White to off-white or light yellow low melting solid
Boiling Point
63 - 65 °C/0.1 mmHg (Lit.)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
tert-Butyl carbazate, Carbonic acid tert-butyl ester hydrazide
CAS Number
870-46-2
Purity
≥ 99% (Assay)
Molecular Formula
C5H12N2O2
Molecular Weight
132.2
MDL Number
MFCD00007593
PubChem ID
70091
Melting Point
35 - 44 °C
Appearance
White to off-white or light yellow low melting solid
Boiling Point
63 - 65 °C/0.1 mmHg (Lit.)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-hydrazide is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: It serves as a key intermediate in the production of various pharmaceutical compounds, enhancing the efficiency of drug development processes.
  • Peptide Synthesis: This compound is crucial in the synthesis of peptides, allowing for the protection of amine groups, which simplifies the overall synthesis and improves yields.
  • Polymer Chemistry: Boc-hydrazide is used in the preparation of polymeric materials, contributing to the development of advanced materials with tailored properties for specific applications.
  • Bioconjugation: It plays a role in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in drug delivery systems.
  • Research in Organic Chemistry: The compound is a valuable reagent in various organic reactions, providing researchers with a versatile tool for exploring new chemical pathways and reactions.

Citations