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Catalog Number:
02200
CAS Number:
3397-35-1
Z-L-leucine-N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-L-Leu-OSu, (S)-Z-2-amino-4-methylpentanoic acid N-hydroxysuccinimide ester
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Product Information

Z-L-leucine-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This ester derivative of leucine is particularly valued for its ability to facilitate the formation of peptide bonds, making it an essential reagent in the development of peptide-based therapeutics and research. Its unique structure enhances reactivity, allowing for efficient coupling reactions, which are crucial in the synthesis of complex peptides and proteins. Researchers in the fields of medicinal chemistry and biochemistry often leverage this compound to create novel peptides with specific biological activities, thereby advancing drug discovery and development.

In addition to its role in peptide synthesis, Z-L-leucine-N-hydroxysuccinimide ester is also employed in the modification of biomolecules, enhancing their stability and bioavailability. Its application extends to the development of targeted drug delivery systems, where it aids in the conjugation of therapeutic agents to carrier molecules. The compound's favorable properties, such as its solubility and stability under physiological conditions, make it a preferred choice for researchers seeking reliable and effective reagents for their studies.

Synonyms
Z-L-Leu-OSu, (S)-Z-2-amino-4-methylpentanoic acid N-hydroxysuccinimide ester
CAS Number
3397-35-1
Purity
≥ 98% (HPLC)
Molecular Formula
C18H22N2O6
Molecular Weight
362.4
MDL Number
MFCD00042759
PubChem ID
102999
Melting Point
115 - 122 ?C
Appearance
White powder
Optical Rotation
[a]D25 = -34 ± 2 º (C=1% in Dioxane)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Z-L-Leu-OSu, (S)-Z-2-amino-4-methylpentanoic acid N-hydroxysuccinimide ester
CAS Number
3397-35-1
Purity
≥ 98% (HPLC)
Molecular Formula
C18H22N2O6
Molecular Weight
362.4
MDL Number
MFCD00042759
PubChem ID
102999
Melting Point
115 - 122 ?C
Appearance
White powder
Optical Rotation
[a]D25 = -34 ± 2 º (C=1% in Dioxane)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-leucine-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, enabling researchers to create complex structures with high specificity and efficiency.
  • Drug Development: Its application in drug formulation helps in improving the solubility and bioavailability of pharmaceutical compounds, making it a key player in the development of new medications.
  • Bioconjugation: The ester functionality allows for selective conjugation with biomolecules, facilitating the creation of targeted therapies and diagnostic agents in the field of biochemistry.
  • Protein Modification: It is used for the modification of proteins, enhancing their stability and functionality, which is crucial in various biotechnological applications.
  • Research in Cancer Therapeutics: The compound is explored for its potential in developing targeted cancer therapies, providing researchers with innovative strategies to combat tumor growth.

Citations