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Catalog Number:
02196
CAS Number:
1738-87-0
Z-L-leucine 4-nitrophenyl ester
Purity:
≥ 98%
Synonym(s):
Z-L-Leu-ONp, (S-Z-2-amino-4-methylpentanoic acid 4-nitrophenyl ester
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Product Information

Z-L-leucine 4-nitrophenyl ester is a valuable compound widely utilized in biochemical research and pharmaceutical applications. This ester derivative of leucine, an essential amino acid, features a nitrophenyl group that enhances its reactivity and solubility, making it an excellent choice for peptide synthesis and drug development. Researchers often leverage its unique properties to create specific peptide sequences, facilitating studies in protein interactions and enzymatic activities. Its ability to serve as a building block in the synthesis of bioactive compounds underscores its significance in medicinal chemistry.

In addition to its role in peptide synthesis, Z-L-leucine 4-nitrophenyl ester is also employed in various analytical applications, including chromatography and mass spectrometry, due to its stability and ease of derivatization. This compound's versatility and effectiveness in enhancing the solubility of peptides make it an essential tool for researchers aiming to explore new therapeutic avenues. With its proven track record in facilitating complex biochemical reactions, Z-L-leucine 4-nitrophenyl ester stands out as a crucial asset in the toolkit of modern chemical research.

Synonyms
Z-L-Leu-ONp, (S-Z-2-amino-4-methylpentanoic acid 4-nitrophenyl ester
CAS Number
1738-87-0
Purity
≥ 98%
Molecular Formula
C20H22N2O6
Molecular Weight
386.4
MDL Number
MFCD00024656
PubChem ID
284201
Melting Point
84-91º C
Optical Rotation
-28 ± 1º (c=1 in Dioxane)
Conditions
Store at 0-8°C
General Information
Synonyms
Z-L-Leu-ONp, (S-Z-2-amino-4-methylpentanoic acid 4-nitrophenyl ester
CAS Number
1738-87-0
Purity
≥ 98%
Molecular Formula
C20H22N2O6
Molecular Weight
386.4
MDL Number
MFCD00024656
PubChem ID
284201
Melting Point
84-91º C
Optical Rotation
-28 ± 1º (c=1 in Dioxane)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-leucine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, enhancing the efficiency of coupling reactions and improving yield.
  • Drug Development: It is used in the design of prodrugs, which can improve the bioavailability of therapeutic agents, making them more effective in treating various conditions.
  • Biochemical Research: Researchers employ this ester in studies related to protein interactions and enzyme activity, providing insights into cellular processes and potential therapeutic targets.
  • Analytical Chemistry: It acts as a standard in chromatographic techniques, helping to calibrate instruments and ensure accurate measurements in complex mixtures.
  • Food Industry: The compound can be explored in flavor enhancement applications, where its properties may contribute to the development of novel food additives.

Citations