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Catalog Number:
02193
CAS Number:
3391-99-9
Z-L-isoleucine-N-hydroxysuccinimide ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Z-L-Ile-OSu
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Product Information

Z-L-isoleucine-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This ester derivative of isoleucine offers enhanced stability and reactivity, making it an ideal choice for researchers looking to develop complex peptide structures. Its unique properties facilitate the formation of peptide bonds, allowing for the efficient coupling of amino acids in various synthetic pathways. This compound is particularly beneficial in the pharmaceutical industry for the development of peptide-based therapeutics, where precise modifications are crucial for efficacy and safety.

In addition to its applications in peptide synthesis, Z-L-isoleucine-N-hydroxysuccinimide ester serves as a valuable tool in the field of biochemistry for the modification of proteins and other biomolecules. Researchers can leverage its reactive nature to create targeted drug delivery systems or to enhance the stability of therapeutic proteins. With its ability to streamline the synthesis process and improve the performance of peptide-based drugs, this compound stands out as a key ingredient for professionals aiming to innovate in drug development and molecular biology.

Synonyms
Z-L-Ile-OSu
CAS Number
3391-99-9
Purity
≥ 99% (HPLC)
Molecular Formula
C18H22N2O6
Molecular Weight
362.4
MDL Number
MFCD00079002
PubChem ID
102994
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -12.5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Z-L-Ile-OSu
CAS Number
3391-99-9
Purity
≥ 99% (HPLC)
Molecular Formula
C18H22N2O6
Molecular Weight
362.4
MDL Number
MFCD00079002
PubChem ID
102994
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -12.5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-isoleucine-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing for the incorporation of isoleucine in various sequences, which is crucial for developing therapeutic peptides.
  • Drug Development: It plays a role in the design of drug candidates, particularly in the pharmaceutical industry, where modifications to amino acids can enhance the efficacy and specificity of drugs.
  • Bioconjugation: The ester functionality enables efficient bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Protein Engineering: This compound is used in studies aimed at modifying protein structures, helping researchers explore the effects of amino acid substitutions on protein function and stability.
  • Diagnostic Applications: Its derivatives are being investigated for use in diagnostic assays, where specific binding interactions can be leveraged to improve the sensitivity and specificity of tests.

Citations