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Catalog Number:
02169
CAS Number:
51644-83-8
Z-D-glutamic acid γ-tert-butyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-D-Glu(OtBu)-OH, Z-D-glutamic acid-5-tert-butyl ester
Documents
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Product Information

Z-D-glutamic acid g-tert-butyl ester is a versatile compound widely utilized in the synthesis of peptides and pharmaceuticals. This derivative of glutamic acid features a tert-butyl ester group, enhancing its solubility and stability, making it an ideal candidate for various chemical reactions. Its unique structure allows for selective modifications, which is particularly beneficial in the development of bioactive molecules. Researchers often leverage this compound in the design of enzyme inhibitors and neurotransmitter analogs, contributing to advancements in drug discovery and development.

In addition to its applications in medicinal chemistry, Z-D-glutamic acid g-tert-butyl ester serves as a valuable building block in organic synthesis. Its ability to undergo various transformations while maintaining structural integrity makes it a preferred choice for chemists looking to create complex molecular architectures. The compound's favorable properties, such as its stability under a range of conditions, further enhance its appeal in both academic and industrial settings, paving the way for innovative solutions in pharmaceuticals and biotechnology.

Synonyms
Z-D-Glu(OtBu)-OH, Z-D-glutamic acid-5-tert-butyl ester
CAS Number
51644-83-8
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO6
Molecular Weight
337.4
MDL Number
MFCD00077018
Melting Point
80 - 90 °C
Appearance
White powder
Optical Rotation
[a]20D = 14 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Z-D-Glu(OtBu)-OH, Z-D-glutamic acid-5-tert-butyl ester
CAS Number
51644-83-8
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO6
Molecular Weight
337.4
MDL Number
MFCD00077018
Melting Point
80 - 90 °C
Appearance
White powder
Optical Rotation
[a]20D = 14 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-D-glutamic acid g-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in creating modified peptides that enhance stability and bioactivity.
  • Pharmaceutical Development: It is used in drug formulation processes, especially in the development of neuroprotective agents and treatments for neurological disorders.
  • Biochemical Research: Researchers utilize it to study glutamate receptors and their role in synaptic transmission, contributing to advancements in understanding brain function.
  • Food Industry: The compound can be explored as a flavor enhancer or additive, providing umami taste while being a safer alternative to traditional glutamates.
  • Cosmetic Formulations: Its properties make it suitable for use in skincare products, where it can enhance moisture retention and skin barrier function.

Citations