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Catalog Number:
02133
CAS Number:
2304-98-5
Nα-Z-Nω-nitro-L-arginine
Purity:
≥ 99% (HPLC)
Synonym(s):
Z-L-Arg(NO2)-OH
Documents
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Product Information

Na-Z-Nw-nitro-L-arginine is a potent nitric oxide synthase inhibitor, primarily utilized in research settings to study the role of nitric oxide in various physiological and pathological processes. This compound is particularly valuable in cardiovascular research, where it aids in understanding the mechanisms of vascular function and the implications of nitric oxide in conditions such as hypertension and atherosclerosis. Its ability to selectively inhibit nitric oxide production makes it an essential tool for researchers investigating the signaling pathways involved in vascular health and disease.

In addition to cardiovascular studies, Na-Z-Nw-nitro-L-arginine has applications in neurobiology, where it helps elucidate the role of nitric oxide in neurotransmission and neurodegenerative diseases. The compound's unique properties allow for targeted investigations into the therapeutic potential of nitric oxide modulation, making it a critical asset for both academic and pharmaceutical research. With its specific action and relevance across multiple fields, Na-Z-Nw-nitro-L-arginine stands out as a key reagent for advancing our understanding of nitric oxide's diverse biological roles.

Synonyms
Z-L-Arg(NO2)-OH
CAS Number
2304-98-5
Purity
≥ 99% (HPLC)
Molecular Formula
C14H19N5O6
Molecular Weight
353.3
MDL Number
MFCD00038092
PubChem ID
102781
Melting Point
145 - 149 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 4 ± 1 ° (C=3 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Z-L-Arg(NO2)-OH
CAS Number
2304-98-5
Purity
≥ 99% (HPLC)
Molecular Formula
C14H19N5O6
Molecular Weight
353.3
MDL Number
MFCD00038092
PubChem ID
102781
Melting Point
145 - 149 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 4 ± 1 ° (C=3 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Z-Nw-nitro-L-arginine is widely utilized in research focused on:

  • Cardiovascular Research: This compound is often used to study nitric oxide synthesis and its effects on blood pressure regulation, helping researchers understand cardiovascular diseases.
  • Neurobiology: It serves as a tool to investigate the role of nitric oxide in neurotransmission, providing insights into neurological disorders and potential therapeutic targets.
  • Pharmacology: Researchers employ this chemical to develop and test new drugs that modulate nitric oxide pathways, which can lead to innovative treatments for various conditions.
  • Biochemistry: It is used in enzyme assays to explore the mechanisms of nitric oxide synthase, enhancing our understanding of metabolic processes.
  • Experimental Therapeutics: The compound is investigated for its potential in treating conditions like hypertension and erectile dysfunction, offering a basis for developing effective therapies.

Citations