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Catalog Number:
02124
CAS Number:
61043-33-2
Z-Ala-Ala-Leu-pNA
Purity:
99%
Synonym(s):
Z-L-alanyl-L-alanyl-L-leucine-4-nitroanilide
Documents
$43.80 /25MG
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Product Information

Z-Ala-Ala-Leu-pNA is a synthetic peptide substrate widely utilized in biochemical research, particularly in the study of proteases and enzyme kinetics. This compound serves as an effective tool for monitoring proteolytic activity due to its unique structure, which includes a p-nitroanilide moiety that releases a chromogenic product upon cleavage. Researchers often employ Z-Ala-Ala-Leu-pNA in assays to quantify enzyme activity, making it invaluable in drug development and diagnostic applications. Its specificity for certain proteases allows for targeted studies, enhancing the understanding of enzyme mechanisms and interactions.

The compound's stability and solubility in various solvents make it suitable for diverse experimental conditions, facilitating its use in both in vitro and in vivo studies. Z-Ala-Ala-Leu-pNA is particularly beneficial in the pharmaceutical industry for screening potential drug candidates that modulate protease activity, providing insights into therapeutic strategies for diseases linked to protease dysfunction. Its ease of use and reliable performance in enzymatic assays position it as a preferred choice among researchers seeking to advance their studies in enzymology and related fields.

Synonyms
Z-L-alanyl-L-alanyl-L-leucine-4-nitroanilide
CAS Number
61043-33-2
Purity
99%
Molecular Formula
C26H33N5O7
Molecular Weight
527.58
MDL Number
MFCD00038759
Conditions
Store at -0°C.
General Information
Synonyms
Z-L-alanyl-L-alanyl-L-leucine-4-nitroanilide
CAS Number
61043-33-2
Purity
99%
Molecular Formula
C26H33N5O7
Molecular Weight
527.58
MDL Number
MFCD00038759
Conditions
Store at -0°C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-Ala-Ala-Leu-pNA is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate in assays to measure the activity of various proteases, helping researchers understand enzyme kinetics and mechanisms.
  • Peptide Synthesis: It is used in the synthesis of peptides, allowing for the exploration of peptide-based therapeutics and their biological activities.
  • Drug Development: The compound plays a role in the development of new drugs, particularly in designing inhibitors that target specific enzymes, which is crucial in pharmaceutical research.
  • Biochemical Research: It aids in studying protein interactions and functions, providing insights into cellular processes and disease mechanisms.
  • Diagnostic Applications: Z-Ala-Ala-Leu-pNA can be utilized in diagnostic tests to detect enzyme-related disorders, offering potential for early diagnosis and treatment strategies.

Citations