Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
01983
Nα-Boc-Nω-(4-toluenesulfonyl)-D-arginine 4-oxymethylphenylacetamidomethyl resin
Synonym(s):
Boc-Nω-(4-toluenesulfonyl)-D-arginine4-oxymethylphenylacetamidomethyl resin, Boc-D-Arg(Tos)-PAM Resin
Documents
$45.47 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Na-Boc-Nw-(4-toluenesulfonyl)-D-arginine 4-oxymethylphenylacetamidomethyl is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to facilitate the introduction of protective groups in peptide chains, which is essential for the selective modification of amino acids. Its unique structure, featuring a Boc (tert-butyloxycarbonyl) protecting group and a toluenesulfonyl moiety, enhances its reactivity and stability, making it an ideal choice for researchers engaged in complex organic synthesis and medicinal chemistry.

In practical applications, this compound is utilized in the development of peptide-based therapeutics, where precise modifications are necessary for achieving desired biological activity. Its compatibility with various coupling reactions allows for the efficient assembly of peptides, which can be critical in the design of novel drugs targeting specific diseases. Additionally, the incorporation of the 4-oxymethylphenylacetamidomethyl group provides further versatility in functionalizing peptides, thereby expanding its utility in pharmaceutical research and development.

Synonyms
Boc-Nω-(4-toluenesulfonyl)-D-arginine4-oxymethylphenylacetamidomethyl resin, Boc-D-Arg(Tos)-PAM Resin
MDL Number
MFCD00801172
Substitution
0.3-0.8
Mesh Size
100-200
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Boc-Nω-(4-toluenesulfonyl)-D-arginine4-oxymethylphenylacetamidomethyl resin, Boc-D-Arg(Tos)-PAM Resin
MDL Number
MFCD00801172
Substitution
0.3-0.8
Mesh Size
100-200
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nw-(4-toluenesulfonyl)-D-arginine 4-oxymethylphenylacetamidomethyl is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the design of peptide-based drugs, particularly in enhancing the stability and bioavailability of therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutics.
  • Research in Cancer Therapy: Its application in developing targeted therapies for cancer treatment showcases its potential in improving treatment efficacy while minimizing side effects.
  • Protein Engineering: This chemical aids in modifying proteins to enhance their functionality, which is vital in biotechnology and pharmaceutical industries.

Citations