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Catalog Number:
01727
CAS Number:
536-33-4
Ethionamide
Purity:
≥ 98% (T)
Synonym(s):
2-Ethylpyridine-4-carbothioamide, 2-Ethylthioisonicotinamide
Documents
$42.46 /5G
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Product Information

Ethionamide is a potent pharmaceutical compound primarily recognized for its application in the treatment of tuberculosis. As an antitubercular agent, it is particularly effective against multidrug-resistant strains of Mycobacterium tuberculosis, making it a critical component in the management of this infectious disease. Ethionamide works by inhibiting the synthesis of mycolic acids, essential components of the bacterial cell wall, thus disrupting the growth and replication of the bacteria. Its unique mechanism of action allows it to be used in combination with other antitubercular drugs, enhancing treatment efficacy and patient outcomes.

In addition to its role in tuberculosis treatment, Ethionamide has shown potential in research settings, particularly in studies focused on drug resistance mechanisms and the development of new therapeutic strategies. Its relevance extends to the pharmaceutical industry, where it serves as a valuable reference compound in drug discovery and development. With its established efficacy and ongoing research into its broader applications, Ethionamide remains a vital compound for both clinical and research purposes.

Synonyms
2-Ethylpyridine-4-carbothioamide, 2-Ethylthioisonicotinamide
CAS Number
536-33-4
Purity
≥ 98% (T)
Molecular Formula
C8H10N2S
Molecular Weight
166.24
MDL Number
MFCD00057361
PubChem ID
2761171
Melting Point
160 - 164 °C
Appearance
Light yellow to yellow to orange powder to crystal
Boiling Point
167 °C/1 mmHg
Conditions
Store at RT
General Information
Synonyms
2-Ethylpyridine-4-carbothioamide, 2-Ethylthioisonicotinamide
CAS Number
536-33-4
Purity
≥ 98% (T)
Molecular Formula
C8H10N2S
Molecular Weight
166.24
MDL Number
MFCD00057361
PubChem ID
2761171
Melting Point
160 - 164 °C
Appearance
Light yellow to yellow to orange powder to crystal
Boiling Point
167 °C/1 mmHg
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ethionamide is widely utilized in research focused on

  • Tuberculosis Treatment: Ethionamide is primarily used as an antibiotic in the treatment of multidrug-resistant tuberculosis, providing an essential option for patients who do not respond to standard therapies.
  • Antimicrobial Research: Researchers use ethionamide to study its effects on various bacterial strains, helping to develop new antimicrobial agents and understand resistance mechanisms.
  • Pharmaceutical Development: It serves as a key compound in the synthesis of new drugs, particularly in the design of anti-infective agents, due to its unique chemical properties.
  • Laboratory Studies: Ethionamide is employed in laboratory settings to investigate its pharmacokinetics and pharmacodynamics, aiding in the optimization of dosing regimens for better patient outcomes.
  • Veterinary Medicine: The compound is also explored for its potential applications in veterinary medicine, particularly for treating infections in livestock, thereby improving animal health and productivity.

Citations