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Catalog Number:
01691
CAS Number:
399-52-0
5-Fluoroindole
Purity:
≥ 99% (HPLC)
Synonym(s):
5-Fluoro-1H-indole
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Product Information

5-Fluoroindole is a versatile chemical compound that has garnered attention in the fields of pharmaceuticals and organic synthesis. This fluorinated derivative of indole is recognized for its unique properties, which make it an essential building block in the development of various bioactive molecules. Its ability to act as a precursor in the synthesis of complex organic compounds allows researchers to explore new pathways in drug discovery and development.

In the pharmaceutical industry, 5-Fluoroindole is particularly valuable for its role in the synthesis of potential therapeutic agents, including those targeting neurological disorders and cancer. Its fluorine atom enhances the compound's metabolic stability and bioavailability, making it a preferred choice for medicinal chemistry applications. Additionally, its incorporation into molecular frameworks can lead to improved pharmacological profiles compared to non-fluorinated analogs. This compound is also utilized in the development of agrochemicals and materials science, showcasing its broad applicability across various sectors.

Synonyms
5-Fluoro-1H-indole
CAS Number
399-52-0
Purity
≥ 99% (HPLC)
Molecular Formula
C8H6FN
Molecular Weight
135.14
MDL Number
MFCD00005671
PubChem ID
67861
Melting Point
45 - 51 °C
Appearance
Almost white to pale yellow powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
5-Fluoro-1H-indole
CAS Number
399-52-0
Purity
≥ 99% (HPLC)
Molecular Formula
C8H6FN
Molecular Weight
135.14
MDL Number
MFCD00005671
PubChem ID
67861
Melting Point
45 - 51 °C
Appearance
Almost white to pale yellow powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluoroindole is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key building block in the synthesis of various pharmaceuticals, particularly in developing new antidepressants and antipsychotics, enhancing therapeutic options for mental health disorders.
  • Biological Research: Researchers use 5-fluoroindole to study its effects on cellular processes, allowing for insights into cancer biology and potential treatments, making it valuable in oncology research.
  • Fluorescent Probes: Its unique properties make it suitable for creating fluorescent probes, which are essential in bioimaging techniques, helping scientists visualize biological processes in real-time.
  • Material Science: The compound is explored in developing advanced materials, such as organic semiconductors, which can be used in electronic devices, offering improved performance over traditional materials.
  • Agrochemical Applications: 5-Fluoroindole is investigated for its potential use in agrochemicals, particularly as a growth regulator, which can enhance crop yields and sustainability in agriculture.

Citations