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Catalog Number:
01397
CAS Number:
76757-92-1
Boc-O-ethyl-D-tyrosine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-D-Tyr(Et)-OH, Boc-D-Phe(4-OEt)-OH, (R-Boc-2-amino-3-(4-ethoxyphenyl)propionic acid
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Product Information

Boc-O-ethyl-D-tyrosine is a versatile amino acid derivative that plays a significant role in peptide synthesis and pharmaceutical research. This compound is particularly valued for its protective Boc (tert-butyloxycarbonyl) group, which facilitates the selective modification of amino acids during the synthesis of complex peptides. Its ethoxy group enhances solubility, making it an ideal choice for various applications in organic synthesis and medicinal chemistry. Researchers utilize Boc-O-ethyl-D-tyrosine in the development of peptide-based therapeutics, where the precise control of amino acid sequences is crucial for achieving desired biological activities.

In addition to its utility in peptide synthesis, Boc-O-ethyl-D-tyrosine is also explored for its potential in drug development, particularly in the design of inhibitors and modulators that target specific biological pathways. Its unique structure allows for the incorporation of D-tyrosine into peptides, which can enhance stability and bioactivity. This compound is an essential tool for chemists and biochemists aiming to create innovative solutions in drug discovery and development.

Synonyms
Boc-D-Tyr(Et)-OH, Boc-D-Phe(4-OEt)-OH, (R-Boc-2-amino-3-(4-ethoxyphenyl)propionic acid
CAS Number
76757-92-1
Purity
≥ 99% (HPLC)
Molecular Formula
C16H23NO5
Molecular Weight
309.4
MDL Number
MFCD00065602
PubChem ID
4395475
Melting Point
81-86 ºC
Appearance
White to off-white powder
Optical Rotation
[α]D20 = +11 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-D-Tyr(Et)-OH, Boc-D-Phe(4-OEt)-OH, (R-Boc-2-amino-3-(4-ethoxyphenyl)propionic acid
CAS Number
76757-92-1
Purity
≥ 99% (HPLC)
Molecular Formula
C16H23NO5
Molecular Weight
309.4
MDL Number
MFCD00065602
PubChem ID
4395475
Melting Point
81-86 ºC
Appearance
White to off-white powder
Optical Rotation
[α]D20 = +11 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-ethyl-D-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require specific amino acid modifications, enhancing the versatility of peptide design.
  • Drug Development: Its unique structure allows for the exploration of new drug candidates, especially in the development of therapeutics targeting neurological disorders, where tyrosine derivatives play a crucial role.
  • Bioconjugation: Boc-O-ethyl-D-tyrosine is used in bioconjugation processes, enabling the attachment of drugs or imaging agents to biomolecules, which is essential in targeted therapy and diagnostics.
  • Research in Neuroscience: The compound is valuable in studies related to neurotransmitter systems, particularly in understanding the role of tyrosine in dopamine synthesis, which is significant for mental health research.
  • Custom Synthesis: Its properties make it an attractive option for custom synthesis in laboratories, allowing researchers to tailor compounds for specific applications in pharmaceuticals and biotechnology.

Citations