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Catalog Number:
01396
CAS Number:
76757-91-0
Boc-O-ethyl-L-tyrosine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Tyr(Et)-OH, Boc-L-Phe(4-OEt)-OH, (S-Boc-2-amino-3-(4-ethoxyphenyl)propionic acid
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Product Information

Boc-O-ethyl-L-tyrosine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and pharmaceutical research. This compound, known for its protective Boc (tert-butyloxycarbonyl) group, enhances the stability and solubility of peptides, making it an essential building block in the development of therapeutic agents. Its ethoxy group contributes to improved lipophilicity, facilitating better membrane permeability and bioavailability in drug formulations. Researchers utilize Boc-O-ethyl-L-tyrosine in the synthesis of various bioactive peptides, including those with potential applications in cancer treatment and neuropharmacology.

The compound's unique properties allow for selective modifications, enabling the design of tailored peptides with specific biological activities. Its ease of use in solid-phase peptide synthesis (SPPS) and compatibility with various coupling reagents make it a preferred choice for chemists in both academic and industrial settings. With its significant role in advancing peptide-based therapeutics, Boc-O-ethyl-L-tyrosine stands out as a valuable asset for researchers aiming to innovate in drug development.

Synonyms
Boc-L-Tyr(Et)-OH, Boc-L-Phe(4-OEt)-OH, (S-Boc-2-amino-3-(4-ethoxyphenyl)propionic acid
CAS Number
76757-91-0
Purity
≥ 98% (HPLC)
Molecular Formula
C16H23NO5
Molecular Weight
309.4
MDL Number
MFCD00065601
PubChem ID
4395475
Melting Point
87 - 91 °C
Appearance
White to off-white solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Tyr(Et)-OH, Boc-L-Phe(4-OEt)-OH, (S-Boc-2-amino-3-(4-ethoxyphenyl)propionic acid
CAS Number
76757-91-0
Purity
≥ 98% (HPLC)
Molecular Formula
C16H23NO5
Molecular Weight
309.4
MDL Number
MFCD00065601
PubChem ID
4395475
Melting Point
87 - 91 °C
Appearance
White to off-white solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-ethyl-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals. Its protective group allows for selective reactions, enhancing the efficiency of peptide formation.
  • Drug Development: Researchers in the pharmaceutical industry leverage Boc-O-ethyl-L-tyrosine to create novel drug candidates, especially those targeting neurological disorders. Its structural properties can improve the bioactivity of compounds.
  • Bioconjugation: This chemical is used in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents, enhancing their specificity and effectiveness in targeted therapies.
  • Research in Neuroscience: It plays a significant role in studies related to neurotransmitter functions, particularly in understanding the role of tyrosine derivatives in brain chemistry and potential treatments for mental health conditions.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of Boc-O-ethyl-L-tyrosine, catering to specific research needs, which provides flexibility and access to tailored compounds for various applications.

Citations