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Catalog Number:
01392
CAS Number:
47375-34-8
Boc-O-tert-butyl-L-tyrosine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-L-Tyr(tBu)-OH, (S)-2-(Boc-amino)-3-(4-tert-butoxyphenyl)propionicacid
Documents
$22.03 /1G
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Product Information

Boc-O-tert-butyl-L-tyrosine is a versatile amino acid derivative widely used in peptide synthesis and pharmaceutical research. This compound features a tert-butyl protective group that enhances its stability and solubility, making it an ideal choice for researchers focusing on the development of complex peptides and proteins. Its unique structure allows for selective reactions, facilitating the incorporation of tyrosine into various peptide sequences, which is crucial for studies in drug design and development.

In addition to its applications in synthetic chemistry, Boc-O-tert-butyl-L-tyrosine is also valuable in the field of biochemistry, particularly in the study of enzyme interactions and protein folding. Researchers appreciate its ability to improve the yield and purity of synthesized peptides, which can lead to more effective therapeutic agents. With its favorable properties and practical applications, Boc-O-tert-butyl-L-tyrosine stands out as a key reagent for professionals in academia and industry alike, driving innovation in peptide-based therapeutics.

Synonyms
Boc-L-Tyr(tBu)-OH, (S)-2-(Boc-amino)-3-(4-tert-butoxyphenyl)propionicacid
CAS Number
47375-34-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H27NO5
Molecular Weight
337.4
MDL Number
MFCD00065598
Melting Point
112 - 118 ºC
Appearance
White powder
Optical Rotation
[a]D20 = -15 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Tyr(tBu)-OH, (S)-2-(Boc-amino)-3-(4-tert-butoxyphenyl)propionicacid
CAS Number
47375-34-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H27NO5
Molecular Weight
337.4
MDL Number
MFCD00065598
Melting Point
112 - 118 ºC
Appearance
White powder
Optical Rotation
[a]D20 = -15 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-tert-butyl-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for selective reactions without affecting the amino acid's functionality. This is particularly beneficial in pharmaceutical development where precise modifications are essential.
  • Drug Development: Its role in modifying drug candidates enhances their stability and bioavailability. Researchers can use it to create prodrugs that improve therapeutic efficacy, especially in cancer treatments.
  • Bioconjugation: The compound is useful in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This application is crucial in creating targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: Boc-O-tert-butyl-L-tyrosine can be used in studies investigating neurotransmitter pathways, aiding in the development of treatments for neurological disorders.
  • Custom Synthesis: Its versatility allows chemists to tailor it for specific applications, making it a valuable tool in custom synthesis projects across various fields, including materials science and biotechnology.

Citations