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Catalog Number:
01385
CAS Number:
13734-40-2
Boc-O-tert-butyl-L-threonine
Purity:
≥ 96% (HPLC)
Synonym(s):
Boc-L-Thr(tBu)-OH
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Product Information

Boc-O-tert-butyl-L-threonine is a valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers looking to streamline their synthesis processes. Its unique structure allows for selective reactions, facilitating the incorporation of L-threonine into peptides, which are crucial for various biological functions and therapeutic applications.

In the pharmaceutical industry, Boc-O-tert-butyl-L-threonine serves as a key building block for the development of bioactive peptides and drug candidates. Its ability to improve the yield and purity of synthesized compounds makes it a preferred choice among chemists. Additionally, its compatibility with various coupling reagents and conditions allows for versatile applications in medicinal chemistry and biochemistry. Researchers can leverage this compound to enhance their workflows and achieve more efficient results in peptide synthesis.

Synonyms
Boc-L-Thr(tBu)-OH
CAS Number
13734-40-2
Purity
≥ 96% (HPLC)
Molecular Formula
C13H25NO5
Molecular Weight
275.3
MDL Number
MFCD00151115
PubChem ID
499095
Melting Point
80 - 100 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 3 ± 1 ° (C=2 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Thr(tBu)-OH
CAS Number
13734-40-2
Purity
≥ 96% (HPLC)
Molecular Formula
C13H25NO5
Molecular Weight
275.3
MDL Number
MFCD00151115
PubChem ID
499095
Melting Point
80 - 100 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 3 ± 1 ° (C=2 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-tert-butyl-L-threonine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of specific sites without affecting others. This is crucial in creating complex peptides for pharmaceuticals.
  • Drug Development: It plays a significant role in the development of new therapeutic agents, particularly in the design of peptide-based drugs, enhancing their stability and bioavailability.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps in attaching biomolecules to other molecules, improving the efficacy of drug delivery systems.
  • Research in Protein Engineering: Researchers utilize it to modify proteins, allowing for the study of protein interactions and functions, which is vital in understanding diseases and developing treatments.
  • Analytical Chemistry: It is employed as a standard in analytical methods, helping in the quantification and characterization of amino acids and peptides in various samples.

Citations