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Catalog Number:
01377
CAS Number:
51154-06-4
Boc-3,4-dehydro-L-proline
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-3,4-dehydro-L-Pro-OH, (S-Boc-2,5-dihydropyrrole-2-carboxylic acid
Hazmat
Documents
$65.50 /100MG
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Product Information

Boc-3,4-dehydro-L-proline is a valuable compound widely utilized in the field of peptide synthesis and medicinal chemistry. This amino acid derivative features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers and professionals engaged in the development of bioactive peptides. Its unique structure allows for the incorporation of dehydroproline into peptides, which can significantly influence the conformational properties and biological activities of the resulting compounds.

In pharmaceutical research, Boc-3,4-dehydro-L-proline has shown promise in the design of peptide-based drugs, particularly in the development of inhibitors for various biological targets. Its ability to modulate peptide conformation can lead to improved binding affinities and selectivities, making it a crucial component in the synthesis of therapeutic agents. Additionally, its applications extend to the fields of materials science and biochemistry, where it can be used to create novel biomaterials and study protein folding mechanisms.

Synonyms
Boc-3,4-dehydro-L-Pro-OH, (S-Boc-2,5-dihydropyrrole-2-carboxylic acid
CAS Number
51154-06-4
Purity
≥ 98% (HPLC)
Molecular Formula
C10H15NO4
Molecular Weight
213.23
MDL Number
MFCD00037896
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -265.0 ± 3º (C=1, in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-3,4-dehydro-L-Pro-OH, (S-Boc-2,5-dihydropyrrole-2-carboxylic acid
CAS Number
51154-06-4
Purity
≥ 98% (HPLC)
Molecular Formula
C10H15NO4
Molecular Weight
213.23
MDL Number
MFCD00037896
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -265.0 ± 3º (C=1, in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3,4-dehydro-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of cyclic peptides that have applications in drug discovery.
  • Pharmaceutical Development: It is used in the design of bioactive molecules, aiding in the creation of new pharmaceuticals that target specific diseases, enhancing efficacy and reducing side effects.
  • Protein Engineering: Researchers employ this compound to modify protein structures, which can lead to improved stability and functionality in therapeutic proteins.
  • Bioconjugation: Its unique structure allows for effective bioconjugation techniques, facilitating the attachment of drugs or imaging agents to biomolecules for targeted therapy.
  • Research in Neuroscience: The compound is investigated for its potential neuroprotective effects, contributing to studies aimed at understanding and treating neurodegenerative diseases.

Citations