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Catalog Number:
01357
CAS Number:
25024-53-7
Nα-Boc-Nim-2,4-dinitrophenyl-L-histidine·isopropanol
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-His(Dnp)-OH·IPA
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Product Information

Na-Boc-Nim-2,4-dinitrophenyl-L-histidine·isopropanol is a versatile compound widely utilized in biochemical research and pharmaceutical applications. This derivative of L-histidine features a dinitrophenyl group, enhancing its reactivity and making it an excellent candidate for various labeling and detection techniques. Its unique structure allows for the selective modification of proteins and peptides, facilitating studies in protein interactions, enzyme activity, and drug development. Researchers often leverage this compound in the synthesis of peptide-based therapeutics, where its protective Boc group provides stability during chemical reactions.

The compound's solubility in isopropanol further enhances its usability in laboratory settings, allowing for easy handling and incorporation into diverse experimental protocols. Its applications extend to the development of biosensors and diagnostic tools, where the dinitrophenyl moiety can serve as a chromogenic or fluorescent tag. With its ability to improve the specificity and sensitivity of assays, Na-Boc-Nim-2,4-dinitrophenyl-L-histidine·isopropanol stands out as a valuable resource for researchers aiming to advance their work in biochemistry and molecular biology.

Synonyms
Boc-L-His(Dnp)-OH·IPA
CAS Number
25024-53-7
Purity
≥ 99% (HPLC)
Molecular Formula
C17H19N5O8·C3H8O
Molecular Weight
481.5
MDL Number
MFCD00076943
PubChem ID
3367519
Melting Point
98 - 123 °C
Appearance
Light yellow powder
Optical Rotation
[a]D20 = 56 ± 3.5 ° (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-His(Dnp)-OH·IPA
CAS Number
25024-53-7
Purity
≥ 99% (HPLC)
Molecular Formula
C17H19N5O8·C3H8O
Molecular Weight
481.5
MDL Number
MFCD00076943
PubChem ID
3367519
Melting Point
98 - 123 °C
Appearance
Light yellow powder
Optical Rotation
[a]D20 = 56 ± 3.5 ° (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-2,4-dinitrophenyl-L-histidine·isopropanol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its unique structure allows for the introduction of specific functional groups that enhance biological activity.
  • Drug Development: In pharmaceutical research, it is used to create targeted drug delivery systems. The dinitrophenyl group can facilitate the attachment of drugs to specific cells, improving efficacy while reducing side effects.
  • Bioconjugation: This chemical is instrumental in bioconjugation processes, where it helps link biomolecules to various carriers. This is particularly useful in creating diagnostic tools and targeted therapies in cancer treatment.
  • Immunology Research: It is applied in the study of immune responses, particularly in the development of vaccines. The compound can be used to modify antigens, enhancing their immunogenicity and effectiveness.
  • Analytical Chemistry: In analytical applications, it aids in the development of assays for detecting specific proteins or enzymes. Its ability to form stable complexes with biomolecules makes it a valuable tool in various analytical techniques.

Citations