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Catalog Number:
01351
CAS Number:
13726-84-6
Boc-L-glutamic acid γ-tert-butyl ester
Purity:
≥ 99.5% (Chiral purity)
Synonym(s):
Boc-L-Glu(OtBu)-OH, Boc-L-glutamic acid 5-tert-butyl ester
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Product Information

Boc-L-glutamic acid g-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of L-glutamic acid offers enhanced stability and solubility, making it an ideal choice for researchers looking to develop complex peptides and proteins. Its unique tert-butyl ester groups provide excellent protection against unwanted reactions during synthesis, allowing for more precise control over the final product. This compound is particularly beneficial in the development of drug candidates, where the integrity of the amino acid structure is crucial for biological activity.

In addition to its role in peptide synthesis, Boc-L-glutamic acid g-tert-butyl ester is also employed in the production of various bioactive compounds and can serve as a building block in the synthesis of pharmaceuticals and agrochemicals. Researchers appreciate its ease of use and compatibility with a range of coupling reagents, which streamlines the synthesis process. The compound's favorable properties not only enhance yield but also improve the overall efficiency of synthetic routes, making it a valuable asset in both academic and industrial laboratories.

Synonyms
Boc-L-Glu(OtBu)-OH, Boc-L-glutamic acid 5-tert-butyl ester
CAS Number
13726-84-6
Purity
≥ 99.5% (Chiral purity)
Molecular Formula
C14H25NO6
Molecular Weight
303.4
MDL Number
MFCD00038257
PubChem ID
294901
Melting Point
108 - 118 ?C
Appearance
White powder
Optical Rotation
[a]20D = -9.5 ± 1 ° (C=2 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Glu(OtBu)-OH, Boc-L-glutamic acid 5-tert-butyl ester
CAS Number
13726-84-6
Purity
≥ 99.5% (Chiral purity)
Molecular Formula
C14H25NO6
Molecular Weight
303.4
MDL Number
MFCD00038257
PubChem ID
294901
Melting Point
108 - 118 ?C
Appearance
White powder
Optical Rotation
[a]20D = -9.5 ± 1 ° (C=2 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamic acid g-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it plays a crucial role in the design of prodrugs, which enhance the bioavailability of active pharmaceutical ingredients, improving therapeutic outcomes.
  • Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in developing targeted drug delivery systems.
  • Research in Neuroscience: It is applied in the synthesis of neurotransmitter analogs, aiding in the study of neurological pathways and potential treatments for neurodegenerative diseases.
  • Material Science: The compound is also explored in creating novel polymers and materials with specific properties, contributing to advancements in fields like coatings and adhesives.

Citations