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Catalog Number:
01348
CAS Number:
30924-93-7
Boc-L-glutamic acid-α-benzyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Glu-OBzl
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Product Information

Boc-L-glutamic acid-a-benzyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of L-glutamic acid features a benzyl ester group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Researchers often leverage its unique properties to facilitate the formation of peptide bonds, enabling the construction of complex peptides and proteins. Its ability to protect the amino group while allowing for selective reactions makes it a valuable tool in the development of bioactive compounds and drug candidates.

In addition to its role in peptide synthesis, Boc-L-glutamic acid-a-benzyl ester is also employed in the production of prodrugs, where its ester functionality can be hydrolyzed to release the active drug. This characteristic is particularly beneficial in enhancing the bioavailability of therapeutic agents. The compound's stability under various conditions further supports its use in both academic and industrial settings, providing researchers with a reliable building block for innovative chemical research and development.

Synonyms
Boc-L-Glu-OBzl
CAS Number
30924-93-7
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO6
Molecular Weight
337.4
MDL Number
MFCD00065568
PubChem ID
3255276
Melting Point
88 - 98 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -30 ± 1 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Glu-OBzl
CAS Number
30924-93-7
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO6
Molecular Weight
337.4
MDL Number
MFCD00065568
PubChem ID
3255276
Melting Point
88 - 98 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -30 ± 1 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamic acid-a-benzyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in creating protected amino acids that facilitate the formation of complex peptide chains.
  • Drug Development: It plays a significant role in medicinal chemistry, aiding in the design of new pharmaceuticals by modifying bioactive compounds to enhance their efficacy and stability.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents, improving targeted delivery and therapeutic outcomes.
  • Research in Neuroscience: Its derivatives are explored for their potential in studying neurotransmitter pathways, contributing to the understanding of various neurological disorders.
  • Cosmetic Formulations: The compound is also being investigated for use in cosmetic products, where it can enhance skin penetration and improve the stability of active ingredients.

Citations